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Isolated elevation of alkaline phosphatase is rare. Herein, we report a case of drug-induced liver injury characterized by isolated alkaline phosphatase elevation for clinicians. Following treatment with ursodeoxycholic acid, the patient achieved complete recovery. Clinicians should recognize that drug-induced liver injury may also present as an isolated elevation of alkaline phosphatase.<\/jats:p>","DOI":"10.1177\/03000605261429248","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T08:03:23Z","timestamp":1773907403000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Terbinafine-induced liver injury with isolated serum alkaline phosphatase elevation: A case report and literature review"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0399-0807","authenticated-orcid":false,"given":"Yi-Hui","family":"Liu","sequence":"first","affiliation":[{"name":"Hangzhou Red Cross Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hangzhou Third Hospital, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Xu","sequence":"additional","affiliation":[{"name":"Hangzhou Red Cross Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Feng","sequence":"additional","affiliation":[{"name":"Hangzhou Red Cross Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Pan","sequence":"additional","affiliation":[{"name":"Hangzhou Red Cross Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"e_1_3_11_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-023-10633-7"},{"key":"e_1_3_11_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/liv.15262"},{"key":"e_1_3_11_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2012.138"},{"key":"e_1_3_11_5_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.34857"},{"key":"e_1_3_11_6_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.02.006"},{"key":"e_1_3_11_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2006.03117.x"},{"key":"e_1_3_11_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gastro.2005.05.006"},{"key":"e_1_3_11_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-017-0547-9"},{"key":"e_1_3_11_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"e_1_3_11_11_2","first-page":"253","article-title":"Guidelines on the management of cholestasis liver diseases (2021)","volume":"30","author":"Chinese Society of Hepatology, Chinese Medical Association","year":"2022","unstructured":"Chinese Society of Hepatology, Chinese Medical Association. 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