{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T02:39:12Z","timestamp":1791859152322,"version":"4.3.4"},"reference-count":109,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Funding","award":["Joint Special Fund of the Department of Science an"],"award-info":[{"award-number":["Joint Special Fund of the Department of Science an"]}]},{"name":"Funding","award":["Key Projects of Yunnan Province Science and Techno"],"award-info":[{"award-number":["Key Projects of Yunnan Province Science and Techno"]}]},{"name":"Funding","award":["Kunming Health Science and Kunming Health Science"],"award-info":[{"award-number":["Kunming Health Science and Kunming Health Science"]}]},{"name":"Funding","award":["Kunming Municipal Health Commission Health Researc"],"award-info":[{"award-number":["Kunming Municipal Health Commission Health Researc"]}]},{"name":"Funding","award":["Kunming Municipal Science and Technology Project ("],"award-info":[{"award-number":["Kunming Municipal Science and Technology Project ("]}]},{"name":"Funding","award":["Science and Technology Program Project of Yunnan P"],"award-info":[{"award-number":["Science and Technology Program Project of Yunnan P"]}]},{"name":"Funding","award":["WuJieping Medical Foundation Clinical Research Spe"],"award-info":[{"award-number":["WuJieping Medical Foundation Clinical Research Spe"]}]},{"name":"Funding","award":["Yunnan Revitalization Talent Support Program (RLQB"],"award-info":[{"award-number":["Yunnan Revitalization Talent Support Program (RLQB"]}]},{"name":"Funding","award":["the National Health Commission Key Laboratory of P"],"award-info":[{"award-number":["the National Health Commission Key Laboratory of P"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:p>With the rapid advancement of sequencing technology, third-generation sequencing, particularly single-molecule real-time sequencing and nanopore sequencing, has opened new avenues for the precise prevention and control of genetic diseases. It offers distinct advantages, including long-read lengths, minimal requirement for extensive polymerase chain reaction amplification, and real-time sequencing capability. This narrative review summarizes and critically evaluates recent advances in the application and latest progress of third-generation sequencing in thalassemia. It focuses on the technical advantages and application status of this technology in detecting complex structural variations, large-scale carrier screening, prenatal diagnosis, and preimplantation genetic testing. The review further analyzes the considerable potential of this technology in improving diagnostic accuracy, shortening detection cycles, and reducing technical costs. Additionally, it discusses the challenges currently faced in data interpretation, standardized processes, and clinical translation. Finally, this review provides insights into future development directions, with the aim of providing new technical perspectives and a theoretical basis for optimizing the prevention and control strategies of thalassemia.<\/jats:p>","DOI":"10.1177\/03000605261444158","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T01:32:50Z","timestamp":1777512770000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Third-generation sequencing technology in the prevention and control of thalassemia: Applications and advances"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-3866-6142","authenticated-orcid":false,"given":"Jian","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Medical Genetics and Prenatal Diagnosis, Kunming Women and Children\u2019s Health Hospital, China"},{"name":"Kunming Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengxin","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics and Prenatal Diagnosis, Kunming Women and Children\u2019s Health Hospital, China"},{"name":"Kunming Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Kunming Medical University"},{"name":"Yunnan Provincial Branch of the National Clinical Research Center for Obstetrics and Gynecology, Kunming Women and Children\u2019s Health Hospital, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maohua","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics and Prenatal Diagnosis, Kunming Women and Children\u2019s Health Hospital, China"},{"name":"Kunming Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiacong","family":"Yan","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Department, First People\u2019s Hospital of Yunnan Province, China"},{"name":"NHC Key Laboratory of Preconception Health Birth in Western China, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Kunming Medical University"},{"name":"Yunnan Provincial Branch of the National Clinical Research Center for Obstetrics and Gynecology, Kunming Women and Children\u2019s Health Hospital, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianping","family":"He","sequence":"additional","affiliation":[{"name":"Department of Medical Genetics and Prenatal Diagnosis, Kunming Women and Children\u2019s Health Hospital, China"},{"name":"Kunming Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)00536-0"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.1788"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.901605"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/03630260903212043"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000518310"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a011742"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-025-06607-4"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.33314\/jnhrc.v20i4.3719"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-024-06007-0"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2025.2548970"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.21037\/atm-22-4309"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2022.146332"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1080\/16078454.2022.2119736"},{"key":"e_1_3_5_15_2","first-page":"385","article-title":"[Expert consensus on the clinical application of single-molecule real-time sequencing in the precise prevention and control of thalassemia (2025 edition)]","volume":"42","author":"Consortium for the Application of Single-Molecule Real-Time Sequencing for the Precision Medicine and Control of Thalassemia, Group of Clinical Genetics Medical Genetics Branch of Chinese Medical Doctor Association","year":"2025","unstructured":"Consortium for the Application of Single-Molecule Real-Time Sequencing for the Precision Medicine and Control of Thalassemia, Group of Clinical Genetics Medical Genetics Branch of Chinese Medical Doctor Association, Wu L. [Expert consensus on the clinical application of single-molecule real-time sequencing in the precise prevention and control of thalassemia (2025 edition)]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2025; 42: 385\u2013396.","journal-title":"Zhonghua Yi Xue Yi Chuan Xue Za Zhi"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-14038-8"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2023.102764"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.7754\/Clin.Lab.2024.240738"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2023.117624"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2022-0299-OA"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2022-0168-OA"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.13512"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.24105"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.4084\/MJHID.2023.026"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.23596"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2022.104091"},{"key":"e_1_3_5_27_2","first-page":"647","article-title":"Thalassemia in Southeast Asia: problems and strategy for prevention and control","volume":"23","author":"Fucharoen S","year":"1992","unstructured":"Fucharoen S, Winichagoon P. Thalassemia in Southeast Asia: problems and strategy for prevention and control. Southeast Asian J Trop Med Public Health 1992; 23: 647\u2013655.","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.13476"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1080\/03630269.2021.2008958"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.17054"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1080\/03630269.2022.2069034"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.942447"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-00967-2"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2023.101074"},{"key":"e_1_3_5_35_2","first-page":"1191","article-title":"Analysis of thalassemia gene mutation types and ethnic distribution characteristics in Hechi area, Guangxi","volume":"32","author":"Liang LF","year":"2024","unstructured":"Liang LF, Huang XN, Li DM, et\u00a0al. Analysis of thalassemia gene mutation types and ethnic distribution characteristics in Hechi area, Guangxi. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2024; 32: 1191\u20131196.","journal-title":"Zhongguo Shi Yan Xue Ye Xue Za Zhi"},{"key":"e_1_3_5_36_2","doi-asserted-by":"publisher","DOI":"10.1080\/03630269.2022.2025825"},{"key":"e_1_3_5_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2022.12.004"},{"key":"e_1_3_5_38_2","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S360320"},{"key":"e_1_3_5_39_2","doi-asserted-by":"publisher","DOI":"10.4084\/MJHID.2023.050"},{"key":"e_1_3_5_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2024.102619"},{"key":"e_1_3_5_41_2","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.18631"},{"key":"e_1_3_5_42_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-023-05191-z"},{"key":"e_1_3_5_43_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12072547"},{"key":"e_1_3_5_44_2","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0000000000001131"},{"key":"e_1_3_5_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.15100"},{"key":"e_1_3_5_46_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0044-1786397"},{"key":"e_1_3_5_47_2","first-page":"Unit7.10","article-title":"Single molecule sequencing with a HeliScope genetic analysis system","volume":"7","author":"Thompson JF","year":"2010","unstructured":"Thompson JF, Steinmann KE. Single molecule sequencing with a HeliScope genetic analysis system. Curr Protoc Mol Biol 2010; Chapter 7: Unit7.10.","journal-title":"Curr Protoc Mol Biol"},{"key":"e_1_3_5_48_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030809"},{"key":"e_1_3_5_49_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abo7651"},{"key":"e_1_3_5_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00511-22"},{"key":"e_1_3_5_51_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-021-01108-x"},{"key":"e_1_3_5_52_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-0904-0_2"},{"key":"e_1_3_5_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gpb.2016.05.004"},{"key":"e_1_3_5_54_2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13030373"},{"key":"e_1_3_5_55_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202215704"},{"key":"e_1_3_5_56_2","doi-asserted-by":"publisher","DOI":"10.1093\/labmed\/lmac065"},{"key":"e_1_3_5_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2022.02.009"},{"key":"e_1_3_5_58_2","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2018-0647"},{"key":"e_1_3_5_59_2","first-page":"434","article-title":"Evaluation of clinical application of gap-PCR as a routine method for alpha-thalassemia carrier detection","volume":"22","author":"Zhou YQ","year":"2002","unstructured":"Zhou YQ, Xiao GF, Li LY, et\u00a0al. Evaluation of clinical application of gap-PCR as a routine method for alpha-thalassemia carrier detection. Di Yi Jun Yi Da Xue Xue Bao 2002; 22: 434\u2013436.","journal-title":"Di Yi Jun Yi Da Xue Xue Bao"},{"key":"e_1_3_5_60_2","first-page":"631","article-title":"[Research progress on the laboratory diagnosis for thalassemia-review]","volume":"26","author":"Fu Y","year":"2018","unstructured":"Fu Y, Liu WJ. [Research progress on the laboratory diagnosis for thalassemia-review]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2018; 26: 631\u2013636.","journal-title":"Zhongguo Shi Yan Xue Ye Xue Za Zhi"},{"key":"e_1_3_5_61_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-36840-8"},{"key":"e_1_3_5_62_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.14059"},{"key":"e_1_3_5_63_2","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.12866"},{"key":"e_1_3_5_64_2","first-page":"257","article-title":"Molecular detection of alpha thalassemia: a review of prevalent techniques","volume":"36","author":"Vijian D","year":"2021","unstructured":"Vijian D, Wan Ab Rahman WS, Ponnuraj KT, et\u00a0al. Molecular detection of alpha thalassemia: a review of prevalent techniques. Medeni Med J 2021; 36: 257\u2013269.","journal-title":"Medeni Med J"},{"key":"e_1_3_5_65_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-019-03119-8"},{"key":"e_1_3_5_66_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.866396"},{"key":"e_1_3_5_67_2","doi-asserted-by":"publisher","DOI":"10.20344\/amp.19162"},{"key":"e_1_3_5_68_2","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.1970"},{"key":"e_1_3_5_69_2","doi-asserted-by":"publisher","DOI":"10.4103\/jpbs.jpbs_838_23"},{"key":"e_1_3_5_70_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.686689"},{"key":"e_1_3_5_71_2","doi-asserted-by":"publisher","DOI":"10.12717\/DR.2023.27.1.9"},{"key":"e_1_3_5_72_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-019-02064-y"},{"key":"e_1_3_5_73_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmoldx.2020.05.004"},{"key":"e_1_3_5_74_2","first-page":"30","article-title":"Third-generation sequencing: the spearhead towards the radical transformation of modern genomics","volume":"12","author":"Athanasopoulou K","year":"2021","unstructured":"Athanasopoulou K, Boti MA, Adamopoulos PG, et\u00a0al. Third-generation sequencing: the spearhead towards the radical transformation of modern genomics. Life (Basel) 2021; 12: 30.","journal-title":"Life (Basel)"},{"key":"e_1_3_5_75_2","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-01499-8"},{"key":"e_1_3_5_76_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/hvac180"},{"key":"e_1_3_5_77_2","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6528\/ac467c"},{"key":"e_1_3_5_78_2","doi-asserted-by":"publisher","DOI":"10.1093\/gpbjnl\/qzae006"},{"key":"e_1_3_5_79_2","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.1076035"},{"key":"e_1_3_5_80_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/hvad073"},{"key":"e_1_3_5_81_2","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2021-0510-OA"},{"key":"e_1_3_5_82_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12920-024-02014-2"},{"key":"e_1_3_5_83_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2022.12.018"},{"key":"e_1_3_5_84_2","doi-asserted-by":"publisher","DOI":"10.1177\/1753495X231207676"},{"key":"e_1_3_5_85_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.23982"},{"key":"e_1_3_5_86_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijlh.13639"},{"key":"e_1_3_5_87_2","doi-asserted-by":"publisher","DOI":"10.1002\/mgg3.2285"},{"key":"e_1_3_5_88_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/hvac223"},{"key":"e_1_3_5_89_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-021-00836-8"},{"key":"e_1_3_5_90_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2024.119749"},{"key":"e_1_3_5_91_2","doi-asserted-by":"publisher","DOI":"10.1080\/16078454.2024.2412949"},{"key":"e_1_3_5_92_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0283668"},{"key":"e_1_3_5_93_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01315-19"},{"key":"e_1_3_5_94_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gpb.2015.08.002"},{"key":"e_1_3_5_95_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-020-02009-9"},{"key":"e_1_3_5_96_2","first-page":"151","article-title":"The human genome project: exploring its progress and successes and the ethical, legal, and social implications","volume":"16","author":"Zneimer SM.","year":"2002","unstructured":"Zneimer SM. The human genome project: exploring its progress and successes and the ethical, legal, and social implications. Clin Leadersh Manag Rev 2002; 16: 151\u2013157.","journal-title":"Clin Leadersh Manag Rev"},{"key":"e_1_3_5_97_2","first-page":"466","article-title":"Ethics and the human genome project","volume":"117","author":"Durfy SJ.","year":"1993","unstructured":"Durfy SJ. Ethics and the human genome project. Arch Pathol Lab Med 1993; 117: 466\u2013469.","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_3_5_98_2","first-page":"35","article-title":"An evaluation of the ethical, legal and social implications program of the U.S. Human Genome Project","volume":"3","author":"Jin J.","year":"2000","unstructured":"Jin J. An evaluation of the ethical, legal and social implications program of the U.S. Human Genome Project. Princet J Bioeth 2000; 3: 35\u201350.","journal-title":"Princet J Bioeth"},{"key":"e_1_3_5_99_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-2819-5_3"},{"key":"e_1_3_5_100_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2024.149187"},{"key":"e_1_3_5_101_2","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2020-0767"},{"key":"e_1_3_5_102_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-022-04637-7"},{"key":"e_1_3_5_103_2","doi-asserted-by":"publisher","DOI":"10.1182\/hematology.2021000296"},{"key":"e_1_3_5_104_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12881-020-0981-x"},{"key":"e_1_3_5_105_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40246-023-00520-5"},{"key":"e_1_3_5_106_2","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2023-0382-OA"},{"key":"e_1_3_5_107_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgg.2025.04.018"},{"key":"e_1_3_5_108_2","doi-asserted-by":"publisher","DOI":"10.1111\/cge.14729"},{"key":"e_1_3_5_109_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-025-06394-y"},{"key":"e_1_3_5_110_2","doi-asserted-by":"publisher","DOI":"10.1080\/16078454.2022.2156720"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605261444158","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605261444158","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605261444158","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:17:03Z","timestamp":1777724223000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605261444158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":109,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1177\/03000605261444158"],"URL":"https:\/\/doi.org\/10.1177\/03000605261444158","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"article-number":"03000605261444158"}}