{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T22:14:28Z","timestamp":1779401668450,"version":"3.53.1"},"reference-count":35,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the Social Development Foundation of Zhenjiang","award":["No. SH2020047"],"award-info":[{"award-number":["No. SH2020047"]}]},{"name":"Scientific Research Project of Health Commission of Jiangsu","award":["No. M2024034"],"award-info":[{"award-number":["No. M2024034"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:p>\n                    Ectopic adrenocorticotropic hormone syndrome is a distinct subtype of endogenous Cushing\u2019s syndrome characterized by excessive cortisol secretion, which increases susceptibility to opportunistic infections. Herein, we present the case of a male patient in his early 40s who was admitted with fatigue and bilateral lower-extremity edema. Laboratory tests revealed markedly elevated serum adrenocorticotropic hormone and cortisol levels. Ectopic adrenocorticotropic hormone syndrome was confirmed via dexamethasone suppression testing and somatostatin receptor\u2013targeted positron emission tomography\u2013computed tomography, which localized an ectopic adrenocorticotropic hormone\u2013secreting right pulmonary carcinoid tumor (a neuroendocrine tumor). During hospitalization, the patient was diagnosed with concurrent\n                    <jats:italic toggle=\"yes\">Pneumocystis jirovecii<\/jats:italic>\n                    pneumonia and pulmonary cryptococcosis, and he responded favorably to trimethoprim\u2013sulfamethoxazole and fluconazole. This case, supported by a review of the relevant literature, highlights the importance of early infection diagnosis, prompt management, and appropriate prophylaxis in patients with ectopic adrenocorticotropic hormone syndrome to improve prognosis.\n                  <\/jats:p>","DOI":"10.1177\/03000605261448078","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T02:25:18Z","timestamp":1779243918000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Ectopic adrenocorticotropic hormone syndrome with\n                    <i>Pneumocystis jirovecii<\/i>\n                    pneumonia and pulmonary cryptococcosis: A case report and literature review"],"prefix":"10.1177","volume":"54","author":[{"given":"Junlan","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Af\ufb01liated People\u2019s Hospital of Jiangsu University, China"},{"name":"Jiangsu University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Af\ufb01liated People\u2019s Hospital of Jiangsu University, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingling","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Af\ufb01liated People\u2019s Hospital of Jiangsu University, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Defei","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Affiliated People\u2019s Hospital of Jiangsu University, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Af\ufb01liated People\u2019s Hospital of Jiangsu University, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1127-9364","authenticated-orcid":false,"given":"Tao","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Af\ufb01liated People\u2019s Hospital of Jiangsu University, China"},{"name":"Department of Respiratory and Critical Care Medicine, Shanghai Tenth People\u2019s Hospital, Tongji University School of Medicine, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"key":"e_1_3_10_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03350337"},{"key":"e_1_3_10_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"e_1_3_10_4_2","first-page":"232","article-title":"Severe ectopic adrenocorticotropic hormone syndrome due to pulmonary carcinoid tumor: a case report and literature review","volume":"10","author":"Aldrete K","year":"2024","unstructured":"Aldrete K, Shahla L. 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