{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T08:05:18Z","timestamp":1781078718212,"version":"3.54.1"},"reference-count":19,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:p>Nail lichen planus is a chronic inflammatory condition that may be isolated to the nail, resulting in longitudinal nail ridging, trachyonychia, and splinter hemorrhages, and may be highly refractory to conventional treatment. The management of nail lichen planus remains challenging because of the lack of standardized treatment guidelines, and the efficacy of existing therapies, both topical and systemic, is often inconsistent or unsatisfactory. Emerging reports have suggested that abrocitinib, a selective Janus kinase 1 inhibitor, may be safe and effective in treating severe nail lichen planus. This report describes the case of a woman in her late 40s with refractory nail lichen planus who was successfully treated with abrocitinib.<\/jats:p>","DOI":"10.1177\/03000605261452882","type":"journal-article","created":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T06:55:30Z","timestamp":1780815330000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Refractory nail lichen planus treated successfully with the Janus kinase 1 inhibitor abrocitinib: A case report"],"prefix":"10.1177","volume":"54","author":[{"given":"Liang","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Dermatology, Daping Hospital, Army Medical University (Third Military Medical University), China"},{"name":"Research Center for Skin Tissue Engineering of Chongqing Higher Education Institutions, Daping Hospital, Army Medical University (Third Military Medical University), China"},{"name":"Department of Dermatology, University-Town Hospital of Chongqing Medical University (The Fourth Clinical College), China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Daping Hospital, Army Medical University (Third Military Medical University), China"},{"name":"Research Center for Skin Tissue Engineering of Chongqing Higher Education Institutions, Daping Hospital, Army Medical University (Third Military Medical University), China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3021-6836","authenticated-orcid":false,"given":"Lingfei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Daping Hospital, Army Medical University (Third Military Medical University), China"},{"name":"Research Center for Skin Tissue Engineering of Chongqing Higher Education Institutions, Daping Hospital, Army Medical University (Third Military Medical University), China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qionghui","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Daping Hospital, Army Medical University (Third Military Medical University), China"},{"name":"Research Center for Skin Tissue Engineering of Chongqing Higher Education Institutions, Daping Hospital, Army Medical University (Third Military Medical University), China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,6]]},"reference":[{"key":"e_1_3_9_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2020.12.002"},{"key":"e_1_3_9_3_2","doi-asserted-by":"publisher","DOI":"10.1159\/000538581"},{"key":"e_1_3_9_4_2","doi-asserted-by":"publisher","DOI":"10.5114\/ada.2020.96298"},{"key":"e_1_3_9_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.02.056"},{"key":"e_1_3_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2022.01.010"},{"key":"e_1_3_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2023.11.024"},{"key":"e_1_3_9_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aav7561"},{"key":"e_1_3_9_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/12034754231156100"},{"key":"e_1_3_9_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2021.5082"},{"key":"e_1_3_9_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2020.4555"},{"key":"e_1_3_9_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1301123"},{"key":"e_1_3_9_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15020385"},{"key":"e_1_3_9_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/all.15969"},{"key":"e_1_3_9_15_2","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S520633"},{"key":"e_1_3_9_16_2","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2024.2434094"},{"key":"e_1_3_9_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"e_1_3_9_18_2","first-page":"758","article-title":"The typical nail lichen planus severity index: an outcome instrument for typical nail lichen planus","volume":"240","author":"He J","year":"2024","unstructured":"He J, Weng T, Zhang W, et\u00a0al. The typical nail lichen planus severity index: an outcome instrument for typical nail lichen planus. 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