{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:09:12Z","timestamp":1792688952107,"version":"4.5.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Special Research Funding Project for High-Quality Development of Hospital Pharmacy and Pharmaceutical Affairs Management in Medical Communities of Zhejiang Pharmaceutical Association","award":["2025ZGYY17"],"award-info":[{"award-number":["2025ZGYY17"]}]},{"name":"Zhejiang Province Medical and Health Science and Technology Planning Project","award":["2025KY641"],"award-info":[{"award-number":["2025KY641"]}]},{"name":"Zhejiang Provincial Natural Science Foundation of China","award":["LYY19H280006"],"award-info":[{"award-number":["LYY19H280006"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:p>This report describes the case of a male in his early 60s with coronary heart disease who developed recurrent urticaria following the initiation of antiplatelet and lipid-lowering therapy. Through sequential drug dechallenge and rechallenge, aspirin was identified as the probable cause. Despite initial treatment with cetirizine and reintroduction of aspirin, the patient\u2019s symptoms recurred, necessitating readmission. A multidisciplinary team, including clinicians and clinical pharmacists, optimized the treatment strategy by replacing aspirin with ticagrelor and cilostazol for antiplatelet therapy, discontinuing and reintroducing atorvastatin to rule out drug allergy, and administering desloratadine citrate and methylprednisolone for antiallergic treatment. The patient\u2019s urticaria resolved completely without recurrence, and aspirin was identified as the probable cause using the adverse drug reaction causality assessment scale. Although aspirin was reintroduced on Day 2, the concurrent use of multiple drugs, including corticosteroids and antihistamines, may have influenced the timing and severity of the subsequent urticaria recurrence. Postdischarge follow-up confirmed sustained remission, highlighting the importance of collaborative care in managing drug-induced urticaria and maintaining cardiovascular safety.<\/jats:p>","DOI":"10.1177\/03000605261453488","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T09:33:23Z","timestamp":1782207203000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Recurrent urticaria induced by aspirin in a post-stent patient: A case study and literature review"],"prefix":"10.1177","volume":"54","author":[{"given":"Yao-Yao","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Pharmacy, The People\u2019s Hospital of Pingyang, China"},{"name":"Center for Clinical Pharmacy, Cancer Center, Department of Pharmacy, Zhejiang Provincial People\u2019s Hospital, Affiliated People\u2019s Hospital, Hangzhou Medical College, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Feng","sequence":"additional","affiliation":[{"name":"Heze Municipal Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu-Cheng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su","family":"Zhang","sequence":"additional","affiliation":[{"name":"Center for Clinical Pharmacy, Cancer Center, Department of Pharmacy, Zhejiang Provincial People\u2019s Hospital, Affiliated People\u2019s Hospital, Hangzhou Medical College, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1556-4365","authenticated-orcid":false,"given":"Kai-Li","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People\u2019s Hospital, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,23]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.abd.2022.08.006"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.794417"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)60615-1"},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.24.3017"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.10.045"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/03000605261431462"},{"key":"e_1_3_8_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1133662"},{"key":"e_1_3_8_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"e_1_3_8_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2011.02557.x"},{"key":"e_1_3_8_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000003667"},{"key":"e_1_3_8_13_2","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S286315"},{"key":"e_1_3_8_14_2","doi-asserted-by":"publisher","DOI":"10.12968\/hmed.2024.0989"},{"key":"e_1_3_8_15_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2003.01228.x"},{"key":"e_1_3_8_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.all.0000235899.57182.d4"},{"key":"e_1_3_8_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2022.07.025"},{"key":"e_1_3_8_18_2","first-page":"512","article-title":"A review of aspirin-exacerbated respiratory diseases and immunological efficacy of aspirin desensitization","volume":"21","author":"Esmaeilzadeh H","year":"2022","unstructured":"Esmaeilzadeh H, Zare M, Alyasin S, et\u00a0al. 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