{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T07:14:51Z","timestamp":1783235691654,"version":"3.54.6"},"reference-count":23,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"\"Pioneer\" and \"Leading Goose\" R&D Program of Zhejiang","award":["2024C03068"],"award-info":[{"award-number":["2024C03068"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>Situs inversus totalis, a rare congenital condition characterized by complete mirror-image transposition of the thoracic and abdominal organs, has not previously been reported in patients with breast cancer. A 60-year-old woman with a 5-year history of left breast nodules was admitted. Contrast-enhanced breast magnetic resonance imaging and abdominal ultrasound revealed mirror-image transposition of the thoracic and abdominal organs. The patient was diagnosed with left breast cancer concomitant with situs inversus totalis. Preimplantation computed tomography revealed that the left internal jugular vein followed a straighter course to the right atrium than the right internal jugular vein. Under ultrasound guidance, a totally implantable venous access port was successfully placed via the left internal jugular vein. Neoadjuvant taxotere adriblastina cyclophosphamide chemotherapy was subsequently administered through the totally implantable venous access port before the patient underwent modified radical mastectomy for left breast cancer. Given the mirror-image anatomy, the anatomically relocated left internal jugular vein should be preferentially selected for totally implantable venous access port placement because of its more favorable anatomical course compared with the right internal jugular vein. To the best of our knowledge, this is the first reported case of totally implantable venous access port implantation in a patient with breast cancer and concurrent situs inversus totalis.<\/jats:p>","DOI":"10.1177\/03000605261463636","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T12:17:54Z","timestamp":1782994674000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Totally implantable venous access port implantation in a breast cancer patient with situs inversus totalis: A case report"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1077-8089","authenticated-orcid":false,"given":"Xuan","family":"Shao","sequence":"first","affiliation":[{"name":"The Second Affiliated Hospital, Zhejiang University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danying","family":"Xu","sequence":"additional","affiliation":[{"name":"The Second Affiliated Hospital, Zhejiang University School of Medicine"},{"name":"Department of Breast Surgery, The Second Hospital of Jiaxing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wuzhen","family":"Chen","sequence":"additional","affiliation":[{"name":"The Second Affiliated Hospital, Zhejiang University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liwei","family":"Pang","sequence":"additional","affiliation":[{"name":"The Second Affiliated Hospital, Zhejiang University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Huang","sequence":"additional","affiliation":[{"name":"The Second Affiliated Hospital, Zhejiang University School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,2]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","unstructured":"Sung H Ferlay J Siegel RL et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2021; 71: 209\u2013249.","DOI":"10.3322\/caac.21660"},{"key":"e_1_3_2_3_2","article-title":"Cancer survival statistics in China 2019\u20132021: a multicenter, population-based study","author":"Zeng H","year":"2024","unstructured":"Zeng H, Zheng R, Sun K, et al. Cancer survival statistics in China 2019\u20132021: a multicenter, population-based study. J Natl Cancer Cent 2024; 4: 203\u2013213.","journal-title":"J Natl Cancer Cent"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.749753"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-02108-4"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2024.155651"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26199328"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26157141"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2023.0031"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2022.03.007"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.01.038"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.2147\/IJGM.S295444"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201506"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/ases.12937"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000000373"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12565-013-0176-z"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1238467"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2022.101815"},{"key":"e_1_3_2_19_2","first-page":"46","article-title":"Coexistence of situs inversus totalis and hepatocellular carcinoma: a series of nine cases and a literature review","volume":"5","author":"Li X","year":"2022","unstructured":"Li X, Fu Z, Zhong J, et al. Coexistence of situs inversus totalis and hepatocellular carcinoma: a series of nine cases and a literature review. J Int Med 2022; 5: 46\u201349.","journal-title":"J Int Med"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S319030"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/humu.22998"},{"key":"e_1_3_2_22_2","doi-asserted-by":"crossref","unstructured":"Wang Y Guo Z Ye B et al. Association of SARS-CoV-2 infection during early weeks of gestation with situs inversus. N Engl J Med 2023; 389: 1722\u20131724.","DOI":"10.1056\/NEJMc2309215"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.4103\/0971-9784.105364"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1177\/02683555211069772"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605261463636","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/03000605261463636","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/03000605261463636","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T06:20:53Z","timestamp":1783232453000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/03000605261463636"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1177\/03000605261463636"],"URL":"https:\/\/doi.org\/10.1177\/03000605261463636","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"article-number":"03000605261463636"}}