{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T04:12:53Z","timestamp":1788667973311,"version":"build-2803163510"},"reference-count":41,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Guangxi Medical University College Student Innovation and Entrepreneurship Project","award":["(No.X202410598380), (No.X202410598383), (No.X2025"],"award-info":[{"award-number":["(No.X202410598380), (No.X202410598383), (No.X2025"]}]},{"name":"Guangxi Medical and Health Appropriate Technology Development and Promotion Application Project","award":["(S2024003)"],"award-info":[{"award-number":["(S2024003)"]}]},{"name":"Basic ability improvement project for young and middle-aged teachers in Guangxi universities","award":["2025KY0124"],"award-info":[{"award-number":["2025KY0124"]}]},{"name":"Guangxi Health Commission self-funded project","award":["No.Z20210117"],"award-info":[{"award-number":["No.Z20210117"]}]},{"name":"Key Laboratory of Breast Cancer Diagnosis and Treatment Research of Guangxi Department of Education."}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine how well shear wave elastography performs as a diagnostic tool for determining the pathological response to neoadjuvant chemotherapy in breast cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Through April 2025, a systematic search of PubMed, MEDLINE, Cochrane Library, China National Knowledge Infrastructure, and SinoMed was used to perform a diagnostic meta-analysis. Included were studies of individuals with breast cancer receiving neoadjuvant chemotherapy with shear wave elastography evaluation. The diagnostic performance of shear wave elastography was assessed using a hierarchical summary receiver operating characteristic model and a bivariate random-effects model. The Quality Assessment of Diagnostic Accuracy Studies-2 was used to evaluate the quality of the study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study includes 15 trials with 1402 patients. For predicting pathological response to neoadjuvant chemotherapy, the pooled sensitivity and specificity of shear wave elastography were 0.68 (95% confidence intervals: 0.49\u20130.86) and 0.73 (95% confidence intervals: 0.60\u20130.87), respectively. 13.06 (95% confidence intervals: 8.42\u201320.25) was the pooled diagnostic odds ratio. The hierarchical summary receiver operating characteristic study showed a moderate diagnostic performance with an area under the curve of 0.85 (95% confidence intervals: 0.82\u20130.88).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Shear wave elastography may be a helpful supplementary imaging modality in clinical treatment monitoring and showed moderate diagnostic performance for assessing pathological response to neoadjuvant chemotherapy in breast cancer. To confirm its clinical value, more extensive prospective investigations are required. PROSPERO registration number: CRD420261435666.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605261474642","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T16:18:34Z","timestamp":1788452314000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Value of shear wave elastography in evaluating response to neoadjuvant chemotherapy in breast cancer: A systematic review and meta-analysis"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8239-1513","authenticated-orcid":false,"given":"Bin","family":"Lian","sequence":"first","affiliation":[{"name":"Guangxi Medical University Cancer Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanxin","family":"Ye","sequence":"additional","affiliation":[{"name":"Guangxi Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengjie","family":"Li","sequence":"additional","affiliation":[{"name":"Guangxi Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huotang","family":"Qin","sequence":"additional","affiliation":[{"name":"Guangxi Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifang","family":"Zhou","sequence":"additional","affiliation":[{"name":"Guangxi Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changyuan","family":"Wei","sequence":"additional","affiliation":[{"name":"Guangxi Medical University Cancer Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huihui","family":"Yang","sequence":"additional","affiliation":[{"name":"People's Hospital of Guangxi Zhuang Autonomous Region"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21442"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.2165\/00044011-200626120-00003"},{"key":"e_1_3_3_4_2","first-page":"51","article-title":"Neo-adjuvant chemotherapy in locally advanced breast cancer: a retrospective analysis from tertiary care centre","volume":"1","author":"Sharma D","year":"2016","unstructured":"Sharma D, Singh G. 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