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Self-management applications are among the potential solutions for controlling and managing these complications. Therefore, this study aimed to design and evaluate a mobile-based application for self-management among patients with lupus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study was conducted in two phases. In the first phase, a systematic review was conducted to identify the information needs of patients and the required capabilities of the application. The identified information needs and capabilities were then confirmed by 12 patients with lupus and six rheumatologists. In the second phase, based on the information and capabilities confirmed in the previous phase, an application prototype was developed and evaluated. To evaluate the application, eight patients with lupus used the application for 1 week. SPSS version 23 was used to analyze the data obtained from both phases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>According to the opinions of patients and physicians, 61 of 70 information items and capabilities met the predefined 75% inclusion threshold and were considered for application design, whereas nine items that scored below this threshold were excluded. The application included four domains: user profile, lifestyle, disease management and control, and application capabilities. Patients rated the usability of the application as good, with a mean score of 7.5 out of 9.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The application developed in this study demonstrated good usability and has the potential to support self-management and self-care among patients with lupus. However, longer-term studies involving larger and more diverse samples are needed to assess sustained use and potential clinical impact.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03000605261495189","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T10:43:56Z","timestamp":1791542636000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Navigating lupus with ease: A patient-driven mobile application for improved self-management"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5730-3972","authenticated-orcid":false,"given":"Khadijeh","family":"Moulaei","sequence":"first","affiliation":[{"name":"Iran University of Medical Sciences"},{"name":"Artificial Intelligence in Medical Sciences Research Center, Smart University of Medical Sciences, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Khajouei","sequence":"additional","affiliation":[{"name":"Fakher Mechatronic Research Center, Kerman University of Medical Sciences, Kerman, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatemeh","family":"Dinari","sequence":"additional","affiliation":[{"name":"Institute for Futures Studies in Health, Kerman University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Ahmadian","sequence":"additional","affiliation":[{"name":"Kerman University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,9]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30237-5"},{"key":"e_1_3_3_3_2","first-page":"472","article-title":"Self-care model application to improve self-care agency, self-care activities, and quality of life in people with systemic lupus erythematosus","volume":"13","author":"Harmayetty SK","year":"2018","unstructured":"Harmayetty SK, Kes M, Efendi F, et al. 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