{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:43:35Z","timestamp":1777725815293,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1973,1,1]],"date-time":"1973-01-01T00:00:00Z","timestamp":94694400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1973,1]]},"abstract":"<jats:p>Tinidazole, a new drug effective against E histolytica, was studied in patients with amoebic liver abscess proved by aspiration of pus.<\/jats:p>\n                  <jats:p>A preliminary open evaluation in fourteen patients provided a cure in all cases. A subsequent comparative study against metronidazole in another twenty-two patients led to a cure in all eleven patients treated with tinidazole and in ten out of eleven patients treated with metronidazole. The response was faster in patients treated with tinidazole. Tinidazole was totally free from side-effects. Tinidazole is a noteworthy addition to anti-amoebic therapy.<\/jats:p>","DOI":"10.1177\/030006057300100208","type":"journal-article","created":{"date-parts":[[2017,1,17]],"date-time":"2017-01-17T19:26:59Z","timestamp":1484681219000},"page":"429-433","source":"Crossref","is-referenced-by-count":3,"title":["Tinidazole and Metronidazole in the Treatment of Amoebic Liver Abscess"],"prefix":"10.1177","volume":"1","author":[{"given":"S N","family":"Mathur","sequence":"first","affiliation":[{"name":"Director of Medical and Health Services, Government of Andhra Pradesh and Ex-Superintendent and Professor and Head of the Department of Medicine, Gandhi Hospital and Medical College, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anantesh","family":"Itigi","sequence":"additional","affiliation":[{"name":"Research Assistant, Department of Medicine, Gandhi Medical College, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Krishnaveni","sequence":"additional","affiliation":[{"name":"Assistant Professor of Medicine, Gandhi Medical College, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vimal","family":"Rai","sequence":"additional","affiliation":[{"name":"Department of Medicine, Gandhi Medical College, Hyderabad, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1973,1,1]]},"reference":[{"key":"bibr1-030006057300100208","unstructured":"Bailey H, Love M (1959) A Short Practice of Surgery, 11th Edition, p 405, Lewis, London."},{"key":"bibr2-030006057300100208","unstructured":"De Esesartc G, Nava C, Reyes J A Garcia (1974) Effect of tinidazolc in amoebiasis.\n                      Abstract of 3rd International Congress of Parasitology\n                      , Munich. August 1974."},{"key":"bibr3-030006057300100208","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197306282882610"},{"key":"bibr4-030006057300100208","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1973.03220240044011"},{"key":"bibr5-030006057300100208","unstructured":"Jeen T (1973) The use of tinidazolc (Fasigyn\n                      \u00ae\n                      ) in the treatment of intestinal and hepatic amoebiasis. Paper read at\n                      Seameo Tropmed Seminar\n                      , Seoul. 29th May to 2nd June 1973, p 22."},{"key":"bibr6-030006057300100208","unstructured":"Jeen T (1974) Use of tinidazolc (Fasigyn\n                      \u00ae\n                      ) in the treatment of intestinal and hepatic amoebiasis.\n                      Abstract of 3rd International Congress of Parasitology\n                      , Munich, August 1974, p 1279."},{"key":"bibr7-030006057300100208","first-page":"361","author":"Mathur S N","year":"1976","journal-title":"Indian Medical Gazette"},{"key":"bibr8-030006057300100208","first-page":"90","volume":"1","author":"Nava C","year":"1974","journal-title":"Investication Medica Internacionale"},{"key":"bibr9-030006057300100208","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1974.03230390047025"},{"key":"bibr10-030006057300100208","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197308162890718"},{"key":"bibr11-030006057300100208","first-page":"93","volume":"211","author":"Zuberi S J","year":"1973","journal-title":"Practitioner"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057300100208","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057300100208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:43:36Z","timestamp":1777459416000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006057300100208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,1]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1973,1]]}},"alternative-id":["10.1177\/030006057300100208"],"URL":"https:\/\/doi.org\/10.1177\/030006057300100208","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,1]]}}}