{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:43:35Z","timestamp":1777725815937,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1973,1,1]],"date-time":"1973-01-01T00:00:00Z","timestamp":94694400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1973,1]]},"abstract":"<jats:p>Sixty patients with symptomatic intestinal amoebiasis were treated for 3 days with a single dose of 2 g of either tinidazole or metronidazole respectively by random order. Tinidazole cured 90% of patients (27\/30) and metronidazole cured 53.3% of patients (16\/30). The difference was significant (p &lt; 0.01). Mild side-effects were reported by 26.7% of patients (8\/30) in the tinidazole group as compared to mild to moderate side effects reported by 53.3% of patients (16\/30) in the metronidazole group. The difference was statistically significant (p&lt;0.05).<\/jats:p>\n                  <jats:p>As the average patient has only a limited understanding and toleration of extended treatment courses, the advantages of a short course employing a single daily dose are obvious. With such a regimen, tinidazole was found to be superior to metronidazole in intestinal amoebiasis.<\/jats:p>","DOI":"10.1177\/030006057300100209","type":"journal-article","created":{"date-parts":[[2017,1,17]],"date-time":"2017-01-17T19:26:59Z","timestamp":1484681219000},"page":"434-437","source":"Crossref","is-referenced-by-count":0,"title":["A Comparison of a Short Course of Single Daily Dosage Therapy of Tinidazole with Metronidazole in Intestinal Amoebiasis"],"prefix":"10.1177","volume":"1","author":[{"given":"N P","family":"Misra","sequence":"first","affiliation":[{"name":"Professor and Head of Department of Medicine, Gandhi Medical College, Bhopal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R C","family":"Gupta","sequence":"additional","affiliation":[{"name":"Research Assistant, Department of Medicine, Gandhi Medical College, Bhopal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1973,1,1]]},"reference":[{"key":"bibr1-030006057300100209","doi-asserted-by":"publisher","DOI":"10.1177\/030006057400200507"},{"key":"bibr2-030006057300100209","first-page":"161","volume":"17","author":"Islam N","year":"1975","journal-title":"Current Therapeutic Research"},{"key":"bibr3-030006057300100209","first-page":"371","volume":"73","author":"Misra N P","year":"1976","journal-title":"Antiseptic"},{"key":"bibr4-030006057300100209","first-page":"1255","volume":"16","author":"Misra N P","year":"1974","journal-title":"Current Therapeutic Research"},{"key":"bibr5-030006057300100209","doi-asserted-by":"publisher","DOI":"10.1080\/00034983.1972.11686814"},{"key":"bibr6-030006057300100209","first-page":"696","volume":"21","author":"Powell S J","year":"1968","journal-title":"The Indian Practitioner"},{"key":"bibr7-030006057300100209","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.9.1.74"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057300100209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057300100209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:43:36Z","timestamp":1777459416000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006057300100209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,1]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1973,1]]}},"alternative-id":["10.1177\/030006057300100209"],"URL":"https:\/\/doi.org\/10.1177\/030006057300100209","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1973,1]]}}}