{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:07:22Z","timestamp":1777727242808,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1977,7,1]],"date-time":"1977-07-01T00:00:00Z","timestamp":236563200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1977,7]]},"abstract":"<jats:p>In a single centre double-blind crossover study in eighteen patients with established rheumatoid disease, a new slow release aspirin (\u201cslow aspirin\u201d) was compared with plain aspirin with respect to patient tolerability and gastric mucosal damage as observed at gastroscopy. \u201cSlow aspirin\u201d was significantly better than plain aspirin with regard to gastroscopic findings. With \u201cslow aspirin\u201d, the gastric mucosal appearances were definitely better in eight patients, worse in two, and eight showed no difference. There was a high incidence of gastric ulceration or erosions in the groups as a whole (39%) but few patients complained of dyspepsia. There was little difference in the ability of both plain and \u201cslow aspirin\u201d in controlling the patients' joint symptoms. Evidence has been provided to suggest that \u201cslow aspirin\u201d is less injurious to the gastric mucosa. In an attempt to reduce gastric mucosal damage due to prolonged aspirin treatment it is therefore concluded that \u201cslow aspirin\u201d merits consideration in the management of chronic rheumatoid disease.<\/jats:p>","DOI":"10.1177\/030006057700500408","type":"journal-article","created":{"date-parts":[[2014,9,4]],"date-time":"2014-09-04T19:38:00Z","timestamp":1409859480000},"page":"270-275","source":"Crossref","is-referenced-by-count":3,"title":["A Comparison of a New Slow Release Aspirin (\u201cSlow Aspirin\u201d) with Plain Aspirin in the Treatment of Rheumatoid Disease"],"prefix":"10.1177","volume":"5","author":[{"given":"D N","family":"Clarke","sequence":"first","affiliation":[{"name":"Medical Registrar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N A G","family":"Mowat","sequence":"additional","affiliation":[{"name":"Consultant Physician, Clinical Senior Lecturer in Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P W","family":"Brunt","sequence":"additional","affiliation":[{"name":"Consultant Physician, Clinical Senior Lecturer in Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L S","family":"Bain","sequence":"additional","affiliation":[{"name":"Consultant Physician, Departments of Rheumatology and Gastro-enterology, Aberdeen Hospitals, Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1977,7,1]]},"reference":[{"key":"bibr1-030006057700500408","doi-asserted-by":"publisher","DOI":"10.1111\/imj.1960.9.2.111"},{"key":"bibr2-030006057700500408","doi-asserted-by":"crossref","unstructured":"British Medical Journal (1976) Less gastric bleeding from aspirin 2, 6","DOI":"10.1136\/bmj.2.6026.6"},{"key":"bibr3-030006057700500408","doi-asserted-by":"publisher","DOI":"10.1136\/gut.10.6.443"},{"key":"bibr4-030006057700500408","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5533.137"},{"key":"bibr5-030006057700500408","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.4038.1143"},{"key":"bibr6-030006057700500408","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)78970-7"},{"key":"bibr7-030006057700500408","doi-asserted-by":"publisher","DOI":"10.1136\/gut.17.5.378"},{"key":"bibr8-030006057700500408","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5882.655"},{"key":"bibr9-030006057700500408","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197405232902102"},{"key":"bibr10-030006057700500408","first-page":"45","volume":"173","author":"Mowat NAG","year":"1975","journal-title":"Quarterly Journal of Medicine"},{"key":"bibr11-030006057700500408","author":"St John DJB","year":"1975","journal-title":"CRC Critical reviews in Toxicology"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057700500408","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057700500408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:48:58Z","timestamp":1777459738000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006057700500408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,7]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1977,7]]}},"alternative-id":["10.1177\/030006057700500408"],"URL":"https:\/\/doi.org\/10.1177\/030006057700500408","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,7]]}}}