{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:07:27Z","timestamp":1777727247673,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1977,7,1]],"date-time":"1977-07-01T00:00:00Z","timestamp":236563200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1977,7]]},"abstract":"<jats:p>An investigation was carried out into the effectiveness of Ovostat E, a low dosage oral contraceptive. One hundred women, aged between 17 and 39 years, participated in the trial; 47 women completed 12 treatment cycles and 42 of these completed all 24 treatment cycles. The following results were obtained by computer analysis:<\/jats:p>\n                  <jats:p>Reliability was 100% and the Pearl Index therefore - 0 Cycle Control length: an obvious regulating effect; 85\u00b73% was the average percentage of women with a cycle length of 26 to 30 days. withdrawal bleeding occurred in 94\u00b76% of cycles duration of withdrawal bleeding: no change in 26\u00b70% 1\u20132 days shorter in 51\u00b7 7% 1\u20132 days longer in 5\u00b76% intensity of withdrawal bleeding: no change in 61\u00b79% decreased in 29\u00b73% increased in 3\u00b74% irregular bleedings occurred in 4\u00b76% of cycles.<\/jats:p>\n                  <jats:p>The most common complaints were nervousness, headache and nausea, the last two virtually disappearing after the 3rd treatment cycle.<\/jats:p>\n                  <jats:p>Of the 49 women who continued the investigation for the further eighteen months, 2 dropped out because of intolerance, 1 because of objections to the periodic check-ups and 1 for reasons unknown.<\/jats:p>","DOI":"10.1177\/030006057700500409","type":"journal-article","created":{"date-parts":[[2014,9,4]],"date-time":"2014-09-04T19:38:00Z","timestamp":1409859480000},"page":"276-280","source":"Crossref","is-referenced-by-count":0,"title":["Critical Dosages for Oral Contraceptives"],"prefix":"10.1177","volume":"5","author":[{"given":"D","family":"Mladenovi\u0107","sequence":"first","affiliation":[{"name":"Director, Gynaecological Hospital, University of Belgrade, Belgrade,                  Jugoslavia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Gr\u010di\u0107","sequence":"additional","affiliation":[{"name":"Head, Clinical Research Department, Gynaecological Hospital, University of                  Belgrade, Belgrade, Jugoslavia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Pestelek","sequence":"additional","affiliation":[{"name":"Research Co-ordinator, Department of Obstetrics & Gynaecology, City Hospital, Subotica, Jugoslavia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Kapor","sequence":"additional","affiliation":[{"name":"Head, Director of Obstetrics & Gynaecology, City Hospital, Subotica, Jugoslavia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1977,7,1]]},"reference":[{"key":"bibr1-030006057700500409","doi-asserted-by":"publisher","DOI":"10.1185\/03007997609109328"},{"key":"bibr2-030006057700500409","first-page":"365","volume":"1","author":"Bergstein NAM","year":"1970","journal-title":"Geneeskundige Gids"},{"key":"bibr3-030006057700500409","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1972.tb46922.x"},{"key":"bibr4-030006057700500409","first-page":"485","volume":"208","author":"Elstein M","year":"1972","journal-title":"Practitioner"},{"key":"bibr5-030006057700500409","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5896.11"},{"key":"bibr6-030006057700500409","doi-asserted-by":"publisher","DOI":"10.1177\/030006057500300609"},{"key":"bibr7-030006057700500409","unstructured":"Pestelek B, Kapor M, Mladenovi\u0107 D, Gr\u010di\u0107 R (1977) Klinische Aspekte eines neuen sehr niedrig               dosierten Kontrazeptivums vom Kombinationstyp f\u00fcr den oralen Gebrauch. To be               published in Fortschritte der Medizin"},{"key":"bibr8-030006057700500409","doi-asserted-by":"publisher","DOI":"10.1016\/S0010-7824(72)80003-9"},{"key":"bibr9-030006057700500409","first-page":"118","volume-title":"Acta Endocrinologica","author":"Schwartz U","year":"1973"},{"key":"bibr10-030006057700500409","first-page":"3351","volume":"23","author":"Tenhaeff D","year":"1971","journal-title":"\u00c4rztliche Praxis"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057700500409","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057700500409","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:48:58Z","timestamp":1777459738000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006057700500409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,7]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1977,7]]}},"alternative-id":["10.1177\/030006057700500409"],"URL":"https:\/\/doi.org\/10.1177\/030006057700500409","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,7]]}}}