{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T10:23:56Z","timestamp":1782728636841,"version":"3.54.5"},"reference-count":8,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1978,1,1]],"date-time":"1978-01-01T00:00:00Z","timestamp":252460800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1978,1]]},"abstract":"<jats:p>Sixty cases of trichomonal vaginitis were randomly allocated to treatment with tinidazole or metronidazole, both administered as a 2 g single dose. One patient on tinidazole did not complete her follow-up. Parasitological cure was obtained in all patients in both the treatment groups. A satisfactory clinical response was obtained in all 29 patients on tinidazole, and in 27 out of 30 (90%) on metronidazole. Complete relief of symptoms was obtained in 62% (18\/29) and 13% (4\/30) of patients on tinidazole and metronidazole, respectively (p&lt;0.01). Ten patients on tinidazole and 24 on metronidazole manifested side-effects. The frequency and severity of side-effects were much more in the metronidazole group (p &lt;0.01). Tinidazole has distinct advantages over metronidazole in the one-dose treatment of trichomonal vaginitis.<\/jats:p>","DOI":"10.1177\/030006057800600108","type":"journal-article","created":{"date-parts":[[2014,9,4]],"date-time":"2014-09-04T18:25:02Z","timestamp":1409855102000},"page":"46-49","source":"Crossref","is-referenced-by-count":16,"title":["Single-Dose Oral Treatment of Vaginal Trichomoniasis with Tinidazole and Metronidazole"],"prefix":"10.1177","volume":"6","author":[{"given":"H T Manorama","family":"Rao","sequence":"first","affiliation":[{"name":"Professor, Department of Obstetrics and Gynaecology, Kasturba Medical College, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D Radhakrishna","family":"Shenoy","sequence":"additional","affiliation":[{"name":"Research Scholar, Department of Obstetrics and Gynaecology, Kasturba Medical College, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1978,1,1]]},"reference":[{"key":"bibr1-030006057800600108","unstructured":"Blacow N W (1972) Martindale The Extra Pharmacopoeia 26th edition, p 1095, The Pharmaceutical Press, London."},{"key":"bibr2-030006057800600108","unstructured":"Brown H C (1969) Basic Clinical Parasitology, 3rd edition, p 41, Appleton-Century-Crofts, New York."},{"key":"bibr3-030006057800600108","first-page":"456","volume":"47","author":"Csonka G W","year":"1971","journal-title":"British Journal of Venereal Diseases"},{"key":"bibr4-030006057800600108","first-page":"261","volume":"1969","author":"Howes H L","year":"1969","journal-title":"Antimicrobial Agents and Chemotherapy"},{"key":"bibr5-030006057800600108","first-page":"525","volume":"48","author":"Morton R S","year":"1972","journal-title":"British Journal of Venereal Diseases"},{"key":"bibr6-030006057800600108","doi-asserted-by":"publisher","DOI":"10.1185\/03007997409113626"},{"key":"bibr7-030006057800600108","first-page":"2128","volume":"22","author":"Welling P G","year":"1972","journal-title":"Arzneimittel-Forschung (Aulendorf)"},{"key":"bibr8-030006057800600108","first-page":"65","volume":"48","author":"Woodcock K R","year":"1972","journal-title":"British Journal of Venereal Diseases"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057800600108","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057800600108","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:49:06Z","timestamp":1777459746000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006057800600108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1978,1]]}},"alternative-id":["10.1177\/030006057800600108"],"URL":"https:\/\/doi.org\/10.1177\/030006057800600108","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,1]]}}}