{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:09:23Z","timestamp":1777727363085,"version":"3.51.4"},"reference-count":5,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1978,5,1]],"date-time":"1978-05-01T00:00:00Z","timestamp":262828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1978,5]]},"abstract":"<jats:p>After the preliminary successful use of injectable lorazepam in calming 20 patients who presented with acute anxiety crises, a formal study of 115 other such patients was carried out. All were seen either in a hospital emergency room or on an emergency out-patient basis in private practice. Treatment consisted of an initial intravenous injection of lorazepam (3 mg) followed, if necessary, by up to three further injections within a 24-hour period. The result was usually dramatic: complete abolition or reasonable control of symptoms within 30 minutes in all but 2 patients. The major effect was relaxant and sedative; 62 patients slept following the injections, although 55 could be easily aroused, 7 could not. Of the other patients, 49 remained awake but relaxed; only 4 remained tense and were regarded as treatment failures. No significant side-effects or changes in vital signs were noted. The results support and extend those reported by other investigators in a recent controlled, double-blind (but otherwise similarly conducted) trial.<\/jats:p>","DOI":"10.1177\/030006057800600304","type":"journal-article","created":{"date-parts":[[2014,9,4]],"date-time":"2014-09-04T18:25:18Z","timestamp":1409855118000},"page":"186-192","source":"Crossref","is-referenced-by-count":0,"title":["Management of Acute Anxiety Syndrome with Parenterally Administered Lorazepam"],"prefix":"10.1177","volume":"6","author":[{"given":"Pedro","family":"G\u00f3mez-Lozano","sequence":"first","affiliation":[{"name":"Clinica San Pedro and San Ignacio University Hospital (Javeriana) Medical School, Bogota, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1978,5,1]]},"reference":[{"key":"bibr1-030006057800600304","doi-asserted-by":"publisher","DOI":"10.1185\/03007997509113639"},{"key":"bibr2-030006057800600304","doi-asserted-by":"publisher","DOI":"10.1007\/BF00437516"},{"key":"bibr3-030006057800600304","first-page":"125","volume":"1","author":"De Paula A J M","year":"1977","journal-title":"Clinical Therapy"},{"key":"bibr4-030006057800600304","doi-asserted-by":"publisher","DOI":"10.1185\/03007997509113687"},{"key":"bibr5-030006057800600304","doi-asserted-by":"publisher","DOI":"10.1185\/03007997509113686"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057800600304","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057800600304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:49:14Z","timestamp":1777459754000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006057800600304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,5]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1978,5]]}},"alternative-id":["10.1177\/030006057800600304"],"URL":"https:\/\/doi.org\/10.1177\/030006057800600304","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,5]]}}}