{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T19:17:28Z","timestamp":1789499848028,"version":"build-2803163510"},"reference-count":7,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1978,9,1]],"date-time":"1978-09-01T00:00:00Z","timestamp":273456000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1978,9]]},"abstract":"<jats:p>A single-blind between-patient study in general practice was made to examine the acceptability and analgesic efficacy of a combination of fenoprofen (200 mg) and paracetamol (500 mg) given 3 to 4 times daily for a period of 4 to 14 days in the treatment of acute and chronic pain. The combination was compared with dihydrocodeine tartrate (30 mg) in two groups of 75 patients suffering from a wide variety of presenting conditions, including osteoarthritis, spondylitis, lumbago,' sciatica, non-articular rheumatism and trauma. Clinical and patient assessment indicated that the combination was an effective analgesic combination, significantly better in success rate than dihydrocodeine tartrate and with a much lower incidence of side-effects (13% of patients receiving fenoprofen and paracetamol reported side-effects compared to 37% for the dihydrocodeine group). The combination demonstrated particular success in the treatment of non-articular rheumatism.<\/jats:p>","DOI":"10.1177\/030006057800600504","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T16:55:45Z","timestamp":1484326545000},"page":"375-380","source":"Crossref","is-referenced-by-count":4,"title":["Analgesic Efficacy and Acceptability of Fenoprofen Combined with Paracetamol and Compared with Dihydrocodeine Tartrate in General Practice"],"prefix":"10.1177","volume":"6","author":[{"given":"J E","family":"Murphy","sequence":"first","affiliation":[{"name":"General Practitioners, Northampton, England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J F","family":"Donald","sequence":"additional","affiliation":[{"name":"General Practitioners, Northampton, England"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A Layes","family":"Molla","sequence":"additional","affiliation":[{"name":"General Practitioners, Northampton, England"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1978,9,1]]},"reference":[{"key":"bibr1-030006057800600504","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-197713040-00001"},{"key":"bibr2-030006057800600504","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6017.1048"},{"key":"bibr3-030006057800600504","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1977.03270390076033"},{"key":"bibr4-030006057800600504","first-page":"1386","volume":"26","author":"Mikulaschek W M","year":"1976","journal-title":"Therapie Woche"},{"key":"bibr5-030006057800600504","doi-asserted-by":"publisher","DOI":"10.1185\/03007997409115243"},{"key":"bibr6-030006057800600504","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600601205"},{"key":"bibr7-030006057800600504","unstructured":"Woodbury D M, Fingl E (1975) in: The Pharmacological Basis of Therapeutics. Editors: Goodman L S, Gilman A (Macmillan: 5th Edition), p 345."}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057800600504","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057800600504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:49:20Z","timestamp":1777459760000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006057800600504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,9]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1978,9]]}},"alternative-id":["10.1177\/030006057800600504"],"URL":"https:\/\/doi.org\/10.1177\/030006057800600504","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,9]]}}}