{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:12:19Z","timestamp":1777727539695,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1979,9,1]],"date-time":"1979-09-01T00:00:00Z","timestamp":304992000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1979,9]]},"abstract":"<jats:p>Status asthmaticus in children is a life-threatening condition that calls for a comprehensive set of therapeutic measures, viz. evacuation of tracheobronchial secretions, parenteral drug administration and improvement of alveolar gas exchange.<\/jats:p>\n                  <jats:p>In the authors' experience, that therapeutic procedure can be much improved by bronchial lavage with mesna. This is illustrated by the good results obtained in fourteen patients with status asthmaticus and in another forty-four cases of global respiratory insufficiency. Evaluation was by blood gas values and X-ray pictures. The method used for bronchial lavage is described.<\/jats:p>","DOI":"10.1177\/030006057900700516","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T13:23:55Z","timestamp":1484141035000},"page":"423-427","source":"Crossref","is-referenced-by-count":2,"title":["The Role of Mesna in the Treatment of Status Asthmaticus in Children"],"prefix":"10.1177","volume":"7","author":[{"given":"V","family":"Kyncl","sequence":"first","affiliation":[{"name":"Anaesthesiology and Resuscitation Clinic, Paediatric Faculty Hospital, Prague \u2013 Motol; UCB \u2013 Pharmaceutical Sector, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Pokorn\u00fd","sequence":"additional","affiliation":[{"name":"Anaesthesiology and Resuscitation Clinic, Paediatric Faculty Hospital, Prague \u2013 Motol; UCB \u2013 Pharmaceutical Sector, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Mega","sequence":"additional","affiliation":[{"name":"Anaesthesiology and Resuscitation Clinic, Paediatric Faculty Hospital, Prague \u2013 Motol; UCB \u2013 Pharmaceutical Sector, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Skondia","sequence":"additional","affiliation":[{"name":"Anaesthesiology and Resuscitation Clinic, Paediatric Faculty Hospital, Prague \u2013 Motol; UCB \u2013 Pharmaceutical Sector, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1979,9,1]]},"reference":[{"key":"bibr1-030006057900700516","volume-title":"Care of the critically ill child","author":"Jones J S","year":"1971"},{"key":"bibr2-030006057900700516","first-page":"163","volume":"7","author":"Kylstra J A","year":"1958","journal-title":"Acta Physiologica Pharmacologica Neerl"},{"key":"bibr3-030006057900700516","first-page":"326","volume":"8","author":"Kylstra J A","year":"1959","journal-title":"Acta Physiologica Pharmacologica Neerl"},{"key":"bibr4-030006057900700516","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.0954-6820.1969.tb07297.x","volume":"185","author":"Lisalo E U M","year":"1969","journal-title":"Acta Medica Scandinavica"},{"key":"bibr5-030006057900700516","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-63-5-819"},{"key":"bibr6-030006057900700516","doi-asserted-by":"publisher","DOI":"10.1378\/chest.62.5_Supplement.95S"},{"key":"bibr7-030006057900700516","first-page":"755","volume":"54","author":"Rogers R M","year":"1970","journal-title":"Med. Clin. Na."},{"key":"bibr8-030006057900700516","first-page":"519","volume":"19","author":"Rogers R M","year":"1971","journal-title":"Clinical Research"},{"key":"bibr9-030006057900700516","first-page":"917","volume":"6","author":"Saunders K B","year":"1974","journal-title":"British Journal of Hospital Medicine"},{"key":"bibr10-030006057900700516","unstructured":"Spi\u010d\u00e1k V, Petru V, Tom\u00e1\u0161kov\u00e1 M (1978) Faktory ovliv\u0148uj\u00edci prognosu d\u011btsk\u00e9ho asthmatu Symposium: Chronicka respira\u010dni onemocn\u011bni u d\u011bti v dlouhodob\u00e9 sledovan\u00ed. Praha 22.5.1978, Karolinum."},{"key":"bibr11-030006057900700516","unstructured":"Vicente G (1928) Sobre una t\u00e9chnica simplificada en la terap\u00e9utica intrapulmonar. Rev. Progr. de la Clin. Julio."},{"key":"bibr12-030006057900700516","first-page":"105","volume":"27","author":"Volejnik J","year":"1972","journal-title":"Cs. pediatric"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057900700516","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006057900700516","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:49:42Z","timestamp":1777459782000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006057900700516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,9]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1979,9]]}},"alternative-id":["10.1177\/030006057900700516"],"URL":"https:\/\/doi.org\/10.1177\/030006057900700516","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,9]]}}}