{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T13:16:38Z","timestamp":1777727798820,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[1981,11,1]],"date-time":"1981-11-01T00:00:00Z","timestamp":373420800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1981,11]]},"abstract":"<jats:p>In a randomized double-blind study fifty-four patients suffering from acute maxillary sinusitis were treated for 10 days with daily doses of sulphadiazine\/trimethopim (1 g) and sulphamethoxazole\/trimethoprim (1.92 g), respectively. The efficacy was evaluated clinically at two follow-up visits. X-ray investigations were performed at admission and after the therapy. Of thirty-nine patients finally evaluated, thirty-seven showed a favourable result. After 6\u20138 days of therapy there was significant difference in cure rates in favour of sulphadiazine\/trimethoprim (p &lt; 0.05) while the outcome as evaluated after treatment was similar for both drugs.<\/jats:p>","DOI":"10.1177\/030006058100900609","type":"journal-article","created":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T06:43:08Z","timestamp":1484462588000},"page":"478-481","source":"Crossref","is-referenced-by-count":2,"title":["Sulphadiazine\/Trimethoprim Once Daily in Maxillary Sinusitis: A Randomized Double-Blind Comparison with Sulphamethoxazole\/Trimethoprim B.I.D."],"prefix":"10.1177","volume":"9","author":[{"given":"Pierre","family":"Federspil","sequence":"first","affiliation":[{"name":"ENT-Clinic of the University of Homburg\/Saar, Federal Republic of Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Bamberg","sequence":"additional","affiliation":[{"name":"ENT-Clinic of the University of Homburg\/Saar, Federal Republic of Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1981,11,1]]},"reference":[{"key":"bibr1-030006058100900609","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1974.03240020053025"},{"key":"bibr2-030006058100900609","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.19.1.82"},{"key":"bibr3-030006058100900609","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.21.2.202"},{"key":"bibr4-030006058100900609","unstructured":"Federspil P (1981) HNO-Indikationen der Trimethoprim-Sulfonamid-Kombinationen. 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