{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:45:38Z","timestamp":1777725938612,"version":"3.51.4"},"reference-count":3,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1982,7,1]],"date-time":"1982-07-01T00:00:00Z","timestamp":394329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1982,7]]},"abstract":"<jats:p>The acceptability of a mixture of meptazinol and hyoscine as a surgical premedication was compared with that of an Omnopon-hyoscine combination in a randomized, double-blind trial involving 101 surgical patients.<\/jats:p>\n                  <jats:p>Blood pressure and respiratory rate were significantly reduced to a similar extent by both premedicant combinations, and this may be interpreted as evidence of a satisfactory alleviation of anxiety by both test mixtures. The two mixtures produced a similar degree of sedation, and both were associated with a useful inhibition of salivary secretion. Side-effects were reported in 25% patients in the meptazinol group, and in 28% of those receiving Omnopon, although a number of these effects may be attributable to hyoscine. There was no difference in the pattern of post-operative analgesic requirements between the two groups, and no unfavourable interaction was noted with any of the anaesthetic agents used.<\/jats:p>","DOI":"10.1177\/030006058201000406","type":"journal-article","created":{"date-parts":[[2017,1,17]],"date-time":"2017-01-17T07:05:44Z","timestamp":1484636744000},"page":"225-228","source":"Crossref","is-referenced-by-count":3,"title":["The Use of Meptazinol as a Premedication for Surgical Patients"],"prefix":"10.1177","volume":"10","author":[{"given":"J","family":"Broadley","sequence":"first","affiliation":[{"name":"Department of Anaesthetics, Kent and Canterbury Hospital, Canterbury, England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Wilson","sequence":"additional","affiliation":[{"name":"Department of Anaesthetics, Kent and Canterbury Hospital, Canterbury, England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Robson","sequence":"additional","affiliation":[{"name":"Wyeth Laboratories, Taplow, Berkshire, England"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1982,7,1]]},"reference":[{"key":"bibr1-030006058201000406","first-page":"523","volume":"2","author":"de Rosayro M","year":"1981","journal-title":"Pharmatherapeutica"},{"key":"bibr2-030006058201000406","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/51.6.497"},{"key":"bibr3-030006058201000406","doi-asserted-by":"publisher","DOI":"10.1016\/0306-3623(78)90002-2"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006058201000406","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006058201000406","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:44:16Z","timestamp":1777459456000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006058201000406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,7]]},"references-count":3,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1982,7]]}},"alternative-id":["10.1177\/030006058201000406"],"URL":"https:\/\/doi.org\/10.1177\/030006058201000406","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,7]]}}}