{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:45:54Z","timestamp":1777725954215,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1982,9,1]],"date-time":"1982-09-01T00:00:00Z","timestamp":399686400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1982,9]]},"abstract":"<jats:p>This study was designed to compare the efficacy and safety of gentamicin otic solution versus colistin-neomycin-hydrocortisone otic suspension in the treatment of otorrhoea due to infection. Fifty-five patients (mean age 36\u00b76 \u00b1 22\u00b71 years) with sixty infected ears with otorrhoea complicating otitis externa, recurrent otitis media with tympanic membrane perforation, or infected mastoid cavities and post-operative tympanoplasties, were treated for 14 days with either an aqueous solution of gentamicin 0\u00b73% or an aqueous suspension of Colistin 0\u00b73%, neomycin 0\u00b733% and hydrocortisone 1\u00b70%. The two possible treatments were assigned randomly and the results were assessed double-blind using usual ordinal scales for monitoring the severity of symptoms. Both otic preparations were found to be equally safe in the treatment of otorrhoea due to infection. No side-effects were observed and hearing status was either unchanged or improved. The antibiotic-steroid combination appeared to be more effective in relieving inflammation in a shorter period of time while gentamicin was observed to be more effective in eradicating the infecting organisms.<\/jats:p>","DOI":"10.1177\/030006058201000504","type":"journal-article","created":{"date-parts":[[2014,9,4]],"date-time":"2014-09-04T18:19:43Z","timestamp":1409854783000},"page":"333-340","source":"Crossref","is-referenced-by-count":19,"title":["The Weeping Ear: Clinical Re-Evaluation of Treatment"],"prefix":"10.1177","volume":"10","author":[{"given":"Maurice C","family":"Gyd\u00e9","sequence":"first","affiliation":[{"name":"Otolaryngologist, Norwood Medical Centre, Winnipeg, Manitoba, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas","family":"Norris","sequence":"additional","affiliation":[{"name":"Director of Microbiology, St. Boniface General Hospital, Winnipeg, Manitoba, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward C","family":"Kavalec","sequence":"additional","affiliation":[{"name":"Pharmacy, Clinical Research Associate, Schering Canada Inc., Pointe Claire, Qu\u00e9bec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1982,9,1]]},"reference":[{"key":"bibr1-030006058201000504","doi-asserted-by":"crossref","unstructured":"Bear V D, Geen A K (1962) Otitis externa: a clinical assessment of a new ear medication. Medical Journal of Australia.","DOI":"10.5694\/j.1326-5377.1962.tb26116.x"},{"key":"bibr2-030006058201000504","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/119.4-5.465"},{"key":"bibr3-030006058201000504","first-page":"459","volume":"91","author":"Gyd\u00e9 M C","year":"1974","journal-title":"Annals of Otolaryngology (Paris)"},{"key":"bibr4-030006058201000504","unstructured":"Gyd\u00e9 M C (1980) Unpublished results."},{"key":"bibr5-030006058201000504","first-page":"854","volume":"70","author":"Lumba S P","year":"1973","journal-title":"Antiseptic"},{"key":"bibr6-030006058201000504","unstructured":"Mawson S R (1963) Diseases of the ear. Edward Arnold Ltd. London, England, p 300."},{"key":"bibr7-030006058201000504","first-page":"786","volume":"203","author":"Mendonca D","year":"1969","journal-title":"The Practitioner"},{"key":"bibr8-030006058201000504","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1966.tb72372.x"},{"key":"bibr9-030006058201000504","unstructured":"Moffet H L (1975) Septic arthritis. Pediatric Infections Journal, 282."},{"key":"bibr10-030006058201000504","unstructured":"Norris D (1980) Personal communications to the author."},{"key":"bibr11-030006058201000504","first-page":"62","volume":"5","author":"Poliquin G","year":"1976","journal-title":"Vie Medical Canadien Francais"},{"key":"bibr12-030006058201000504","first-page":"298","volume":"5","author":"Poliquin G","year":"1976","journal-title":"Journal of Otolaryngology"},{"key":"bibr13-030006058201000504","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-196601000-00019"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006058201000504","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006058201000504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:44:18Z","timestamp":1777459458000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006058201000504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,9]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1982,9]]}},"alternative-id":["10.1177\/030006058201000504"],"URL":"https:\/\/doi.org\/10.1177\/030006058201000504","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,9]]}}}