{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:33:27Z","timestamp":1787164407467,"version":"build-2736575974"},"reference-count":6,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1984,9,1]],"date-time":"1984-09-01T00:00:00Z","timestamp":462844800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1984,9]]},"abstract":"<jats:p>The antipyretic activity of Ibuprofen and aspirin was compared in sixteen children with pyrexia due to upper respiratory tract infection and in twelve with fever due to other causes. All 28 children received ibuprofen (7 mg\/kg of body-weight) and aspirin (15 mg\/kg of body-weight) in a single dose on 2 consecutive days in a crossover manner. Rectal temperature was recorded prior to and at regular intervals up to 8 hours after drug administration.<\/jats:p>\n                  <jats:p>Analysis of the results indicate that ibuprofen and aspirin effectively lower temperature and the two drugs are comparable in their antipyretic activity. In conclusion, significant antipyretic activity, good tolerance profile and availability in syrup form make ibuprofen a useful substitute for aspirin in children with fever.<\/jats:p>","DOI":"10.1177\/030006058401200505","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T03:57:53Z","timestamp":1484107073000},"page":"292-297","source":"Crossref","is-referenced-by-count":17,"title":["Comparative Evaluation of Antipyretic Activity of Ibuprofen and Aspirin in Children with Pyrexia of Varied Aetiology"],"prefix":"10.1177","volume":"12","author":[{"given":"P W","family":"Kandoth","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Seth GS Medical College & KEM Hospital, Bombay, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M K","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Seth GS Medical College & KEM Hospital, Bombay, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V R","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Seth GS Medical College & KEM Hospital, Bombay, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R S","family":"Satoskar","sequence":"additional","affiliation":[{"name":"Department of Pharmacology & Clinical Pharmacology Unit, Seth GS Medical College & KEM Hospital, Bombay, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1984,9,1]]},"reference":[{"key":"bibr1-030006058401200505","volume":"9","author":"Adams S S","year":"1970","journal-title":"Rheumatology and Physical Medicine Supplement"},{"key":"bibr2-030006058401200505","doi-asserted-by":"publisher","DOI":"10.1016\/S0307-742X(21)00075-8"},{"key":"bibr3-030006058401200505","first-page":"659","volume":"211","author":"Ansell B M","year":"1973","journal-title":"Practitioner"},{"key":"bibr4-030006058401200505","unstructured":"Cohen S N, Strebel L (1979) Nelson Textbook of Paediatrics. Nelson W E (Editor), 11th Ed, W B Saunders Company. p 2056."},{"key":"bibr5-030006058401200505","first-page":"579","volume":"21","author":"Gaitonde B B","year":"1973","journal-title":"Journal of the Association of Physicians of India"},{"key":"bibr6-030006058401200505","unstructured":"Menon N D, Whelton J J, Ansell B M, Goldberg A A J A A J (1973) A comparative study of ibuprofen and aspirin in Still's disease (juvenile chronic polyarthritis).\n                      Abstracts of papers on ibuprofen and flurbiprofen, XIII International Congress of Rheumatology, Kyoto, Japan. Current Medical Research and Opinion, London\n                      , 1974, p 17."}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006058401200505","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006058401200505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:44:48Z","timestamp":1777459488000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006058401200505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,9]]},"references-count":6,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1984,9]]}},"alternative-id":["10.1177\/030006058401200505"],"URL":"https:\/\/doi.org\/10.1177\/030006058401200505","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,9]]}}}