{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:23:31Z","timestamp":1777724611372,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1990,9,1]],"date-time":"1990-09-01T00:00:00Z","timestamp":652147200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1990,9]]},"abstract":"<jats:p>In a 4-week, double-blind, randomized, parallel study to compare the efficacy of cetirizine and astemizole, 47 patients with chronic idiopathic urticaria were enrolled, with 19 cetirizine- and 17 astemizole-treated patients being taken into account for final analysis. Both treatment groups were comparable at initial visit. Giant weals, weals, erythema and oedema were improved in both treatment groups after treatment for 1 \u2013 4 weeks. Patients' evaluation using a visual analogue scale and symptom scores assessed on a four-point scale showed that the improvement was significantly better using cetirizine for weals ( P = 0.04) and there was a trend ( P = 0.09) in favour of cetirizine for the visual analogue scale. The number and severity of side-effects were similar in both treatment groups.<\/jats:p>","DOI":"10.1177\/030006059001800503","type":"journal-article","created":{"date-parts":[[2017,1,16]],"date-time":"2017-01-16T04:49:54Z","timestamp":1484542194000},"page":"358-365","source":"Crossref","is-referenced-by-count":25,"title":["Cetirizine vs Astemizole in the Treatment of Chronic Idiopathic Urticaria"],"prefix":"10.1177","volume":"18","author":[{"given":"A.","family":"Alomar","sequence":"first","affiliation":[{"name":"Department of Dermatology, Santa Creu i Sant Pau Hospital, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"De La Cuadra","sequence":"additional","affiliation":[{"name":"Valencia Hospital, Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Princess Hospital, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1990,9,1]]},"reference":[{"key":"bibr1-030006059001800503","first-page":"235","volume":"59","author":"Rihoux JP","year":"1987","journal-title":"Ann Allergy"},{"key":"bibr2-030006059001800503","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(86)80114-2"},{"key":"bibr3-030006059001800503","doi-asserted-by":"publisher","DOI":"10.1177\/030006058901700103"},{"key":"bibr4-030006059001800503","first-page":"265","volume":"15","author":"Rihoux JP","year":"1989","journal-title":"Acta Ther"},{"key":"bibr5-030006059001800503","unstructured":"Lobaton P, Moreno F, Coulie P: Cetirizine versus astemizole in the treatment of perennial allergic rhinitis and study of the concomitant effect on various histamine and allergen-induced responses. Ann Allergy; in press."},{"key":"bibr6-030006059001800503","first-page":"13","volume-title":"Focus on Astemizole in Chronic Urticaria.","author":"Paul E","year":"1985"},{"key":"bibr7-030006059001800503","first-page":"679","volume":"4","author":"Cainelli T","year":"1986","journal-title":"Pharmatherapeutica"},{"key":"bibr8-030006059001800503","unstructured":"Lambert D, Bloom M, Beaumont D, Double-blind comparative study of terfenadine versus astemizole efficacy, onset of action, and tolerance in idiopathic chronic urticaria (Abstract).\n                      XIVth Congress of the European Academy of Allergy and Clinical Immunology\n                      , Berlin, 17\u201322 September 1989."},{"key":"bibr9-030006059001800503","first-page":"10","volume-title":"Focus on Astemizole in Chronic Urticaria.","author":"Mobacken H","year":"1985"},{"key":"bibr10-030006059001800503","first-page":"77","volume":"15","author":"Go MJTH","year":"1989","journal-title":"Acta Ther"},{"key":"bibr11-030006059001800503","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1988.tb07103.x"},{"key":"bibr12-030006059001800503","first-page":"65","volume":"15","author":"Kint A","year":"1989","journal-title":"Acta Ther"},{"key":"bibr13-030006059001800503","unstructured":"MacHer E, Eichelberg D: Terfenadine and cetirizine in chronic idiopathic urticara (Abstract).\n                      XIVth Congress of the European Academy of Allergy and Clinical Immunology\n                      , Berlin, 17\u201322 September 1989."},{"key":"bibr14-030006059001800503","first-page":"367","volume":"9","author":"Lantin JP","year":"1988","journal-title":"New Engl Reg Allergy Proc"},{"key":"bibr15-030006059001800503","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1987.tb02027.x"},{"key":"bibr16-030006059001800503","first-page":"11","volume":"3","author":"Fadel R","year":"1989","journal-title":"Health Sci Rev"},{"key":"bibr17-030006059001800503","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(88)90058-9"},{"key":"bibr18-030006059001800503","first-page":"67","volume":"59","author":"Michel L","year":"1987","journal-title":"Ann Allergy"},{"key":"bibr19-030006059001800503","first-page":"14","volume":"3","author":"Michel L","year":"1989","journal-title":"Health Sci Rev"},{"key":"bibr20-030006059001800503","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90104-8"},{"key":"bibr21-030006059001800503","doi-asserted-by":"publisher","DOI":"10.1159\/000234641"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006059001800503","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006059001800503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:40:20Z","timestamp":1777459220000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006059001800503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,9]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1990,9]]}},"alternative-id":["10.1177\/030006059001800503"],"URL":"https:\/\/doi.org\/10.1177\/030006059001800503","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,9]]}}}