{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:27:30Z","timestamp":1777724850511,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1992,2,1]],"date-time":"1992-02-01T00:00:00Z","timestamp":696902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1992,2]]},"abstract":"<jats:p>\n                    Plasma concentrations of adrenocorticotrophic hormone, Cortisol, 17-hydroxyprogesterone, testosterone, \u0394\n                    <jats:sup>4<\/jats:sup>\n                    -androstenedione and dehydroepiandrosterone sulphate were determined in 10 regularly menstruating hirsute women 0, 15, 30, 60, 90 and 120 min after intravenous injection of 100 \u03bcg corticotrophin releasing factor. The baseline concentrations of adrenocorticotrophic hormone, Cortisol, progesterone and dehydroepiandrosterone sulphate were within the normal range, whereas the mean \u0394\n                    <jats:sup>4<\/jats:sup>\n                    -androstenedione and testosterone concentrations were mildly elevated. The administration of corticotrophin releasing factor induced a rapid and significant increase in plasma concentrations of adrenocorticotrophic hormone, Cortisol, 17-hydroxyprogesterone and \u0394\n                    <jats:sup>4<\/jats:sup>\n                    -androstenedione after 60 min, whereas dehydroepiandrosterone sulphate and testosterone concentrations were not significantly elevated. These findings suggest that the corticotrophin releasing factor test can readily be used as an out-patient procedure to exclude adrenal hirsutism.\n                  <\/jats:p>","DOI":"10.1177\/030006059202000105","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T17:51:23Z","timestamp":1484157083000},"page":"40-44","source":"Crossref","is-referenced-by-count":0,"title":["The Corticotrophin Releasing Factor Test: A Valuable and Rapid Procedure for the Differential Diagnosis of Hirsutism"],"prefix":"10.1177","volume":"20","author":[{"given":"S","family":"Georgala","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Schulpis","sequence":"additional","affiliation":[{"name":"Department of Dermatology, \u2018A. Syngros' Hospital, University of Athens, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Tolis","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, \u2018Hippocration\u2019 Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1992,2,1]]},"reference":[{"key":"bibr1-030006059202000105","doi-asserted-by":"publisher","DOI":"10.1210\/endo-57-5-599"},{"key":"bibr2-030006059202000105","doi-asserted-by":"publisher","DOI":"10.1139\/o55-054"},{"key":"bibr3-030006059202000105","first-page":"2087","volume":"36","author":"Sayers G","year":"1977","journal-title":"Fed Proc"},{"key":"bibr4-030006059202000105","doi-asserted-by":"publisher","DOI":"10.1126\/science.6267699"},{"key":"bibr5-030006059202000105","doi-asserted-by":"publisher","DOI":"10.1210\/endo-110-1-272"},{"key":"bibr6-030006059202000105","first-page":"927","author":"Grossman A","year":"1982","journal-title":"Lancet"},{"key":"bibr7-030006059202000105","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-57-5-963"},{"key":"bibr8-030006059202000105","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-39-2-340"},{"key":"bibr9-030006059202000105","first-page":"267","volume":"108","author":"Frank K","year":"1985","journal-title":"Acta Endocrinol (Copenh"},{"key":"bibr10-030006059202000105","first-page":"264","volume":"105","author":"Dorr HC","year":"1984","journal-title":"Acta Endocrinol (Copenh"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006059202000105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006059202000105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:40:56Z","timestamp":1777459256000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006059202000105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,2]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1992,2]]}},"alternative-id":["10.1177\/030006059202000105"],"URL":"https:\/\/doi.org\/10.1177\/030006059202000105","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,2]]}}}