{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:33:51Z","timestamp":1777725231596,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1996,1,1]],"date-time":"1996-01-01T00:00:00Z","timestamp":820454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:p>A 59-year-old patient with schizophrenia developed Sj\u00f6gren's syndrome. She also presented with the lupus anticoagulant attributed to long-term medication with chlorpromazine. Serial plasmapheresis treatments were performed to decrease the anti-coagulant activity. As a result, the activated partial thromboplastin time was temporarily improved, but the lupus anti-coagulant activity did not change. Because of her unstable emotional state, she continued to require chlorpromazine, but took a low dose of aspirin (87 mg\/day) and never manifested any signs of thrombotic events. In view of the potential anti-thrombotic effects of chlorpromazine, it may not be necessary to use plasmapheresis in an attempt to reduce anti-coagulant activity among patients with chlorpromazine-induced lupus anti-coagulant.<\/jats:p>","DOI":"10.1177\/030006059602400119","type":"journal-article","created":{"date-parts":[[2017,1,18]],"date-time":"2017-01-18T01:35:36Z","timestamp":1484703336000},"page":"147-150","source":"Crossref","is-referenced-by-count":3,"title":["Plasmapheresis for a Schizophrenic Patient with Drug-Induced Lupus Anti-Coagulant"],"prefix":"10.1177","volume":"24","author":[{"given":"Y","family":"Matsukawa","sequence":"first","affiliation":[{"name":"First Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Satoh","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Nihon University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Itoh","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Nishinarita","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Horie","sequence":"additional","affiliation":[{"name":"First Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Nihon University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Nihon University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Kojima","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Nihon University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1996,1,1]]},"reference":[{"key":"bibr1-030006059602400119","doi-asserted-by":"crossref","unstructured":"Gold JE, Haubenstock A, Zalusky R: Lupus anticoagulant and AIDS. 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Lupus 1994; 3: 31\u201335","DOI":"10.1177\/096120339400300107"},{"key":"bibr8-030006059602400119","first-page":"283","volume":"5","author":"Matsukawa Y","year":"1994","journal-title":"Jpn J Rheumatol"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006059602400119","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030006059602400119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:41:50Z","timestamp":1777459310000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030006059602400119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1177\/030006059602400119"],"URL":"https:\/\/doi.org\/10.1177\/030006059602400119","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1]]}}}