{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:01:00Z","timestamp":1777917660496,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2000,7,1]],"date-time":"2000-07-01T00:00:00Z","timestamp":962409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2000,7]]},"abstract":"<jats:p>\n                    The accuracy of the sentinel node technique in the evaluation of axillary node involvement in breast cancer was evaluated in 83 consecutive patients with monofocal T\n                    <jats:sub>1\u20132<\/jats:sub>\n                    carcinoma, who were clinically N\n                    <jats:sub>0<\/jats:sub>\n                    and who underwent lymphoscintigraphy with\n                    <jats:sup>99m<\/jats:sup>\n                    Tc-colloid integrated with intraoperative sentinel node detection by a portable probe. Lymphoscintigraphy revealed at least one sentinel node in 75 patients (90.4%), always identified by the probe. In eight patients (9.6%) the sentinel node was detected neither by lymphoscintigraphy nor by the probe. All removed lymph nodes were analyzed by hematoxylin-eosin histology and the sentinel node by immunostaining. In 28\/75 patients (37.3%) at least one metastatic axillary lymph node was detected; in 16 of the 28 N+ subjects (57%) only the sentinel node was positive. The false negative rate (sentinel node negative\/other axillary lymph nodes positive) was 17.85% (5\/28 patients). In 9\/23 patients (39%) micrometastases were found in the sentinel node only. In conclusion, specific sentinel node positivity in 57% of cases supports the validity of the sentinel node concept. Moreover, nine patients would have been considered No by standard hematoxylin-eosin histology without sentinel node-aided immunostaining. A 17.8% false negative rate calls for caution in patients with negative sentinel nodes.\n                  <\/jats:p>","DOI":"10.1177\/030089160008600412","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:37:07Z","timestamp":1523882227000},"page":"309-311","source":"Crossref","is-referenced-by-count":3,"title":["Sentinel Node Biopsy in Breast Cancer: The Experience of Brescia Civic Hospital"],"prefix":"10.1177","volume":"86","author":[{"given":"Claudio","family":"Pizzocaro","sequence":"first","affiliation":[{"name":"Divisione di Medicina Nucleare, Spedali Civili, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pier Luigi","family":"Rossini","sequence":"additional","affiliation":[{"name":"Divisione di Medicina Nucleare, Spedali Civili, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arturo","family":"Terzi","sequence":"additional","affiliation":[{"name":"Divisione di Medicina Nucleare, Spedali Civili, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Farfaglia","sequence":"additional","affiliation":[{"name":"Secondo Reparto di Chirurgia, Spedali Civili, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Lazzari","sequence":"additional","affiliation":[{"name":"Secondo Reparto di Chirurgia, Spedali Civili, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edda","family":"Simoncini","sequence":"additional","affiliation":[{"name":"Divisione di Oncologia Medica, Spedali Civili, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raffaele","family":"Giubbini","sequence":"additional","affiliation":[{"name":"Divisione di Medicina Nucleare, Spedali Civili, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2000,7,1]]},"reference":[{"key":"bibr1-030089160008600412","first-page":"2080","volume":"39","author":"De Cicco C.","year":"1998","journal-title":"J. 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