{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T14:25:03Z","timestamp":1792074303248,"version":"4.4.0"},"reference-count":5,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2000,7,1]],"date-time":"2000-07-01T00:00:00Z","timestamp":962409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2000,7]]},"abstract":"<jats:p>We report the preliminary results obtained with the intraoperative MIBI-guided gamma probe in a group of 9 patients with primary hyperparathyroidism (pHPT). These patients were selected for limited invasive parathyroid surgery on the basis of a preoperative imaging protocol consisting of a pertechnetate &amp; perchlorate\/MIBI scan combined with neck ultrasonography (US). In the operating room 50\u201370 MBq MIBI was injected 30 to 45 min before parathyroidectomy. The radioactivity was measured intraoperatively at three sites: parathyroid (P), thyroid (T), and background (B). The P\/B, P\/T, and T\/B ratios were calculated. The T\/B ratio was relatively constant (range, 1.5\u20131.8; mean, 1.6), while a wide variability was observed both for P\/T ratio (range, 1.2\u20132.3; mean, 1.7) and P\/B ratio (range, 2.1\u20134.0; mean, 2.9). At surgery single enlarged parathyroid glands were easily identified by means of intraoperative MIBI-guided gamma probe. Moreover, the gamma probe allowed us to perform a limited 2\u20132.5 cm neck incision in eight patients affected by parathyroid adenoma. In the remaining patient a parathyroid carcinoma was diagnosed and a bilateral neck exploration was performed. The intraoperative MIBI gamma probe seems to be a useful aid when limited invasive parathyroid surgery is performed.<\/jats:p>","DOI":"10.1177\/030089160008600434","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:37:07Z","timestamp":1523882227000},"page":"370-371","source":"Crossref","is-referenced-by-count":8,"title":["<sup>99m<\/sup>\n                    Tc-MIBI Radioguided Surgery for Limited Invasive Parathyroidectomy"],"prefix":"10.1177","volume":"86","author":[{"given":"Dario","family":"Casara","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine and University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Rubello","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Piotto","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Carretto","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Rosa","family":"Pelizzo","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine and University of Padova, Padova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2000,7,1]]},"reference":[{"key":"bibr1-030089160008600434","doi-asserted-by":"publisher","DOI":"10.1177\/019459989010200602"},{"key":"bibr2-030089160008600434","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800800414"},{"key":"bibr3-030089160008600434","first-page":"840","volume":"38","author":"O'Doherty M.J.","year":"1997","journal-title":"J. Nucl. Med.,"},{"key":"bibr4-030089160008600434","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197602000-00010"},{"key":"bibr5-030089160008600434","first-page":"994","volume":"26","author":"Rubello D.","year":"1999","journal-title":"Eur. J. Nucl. Med.,"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089160008600434","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089160008600434","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:19:49Z","timestamp":1777659589000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030089160008600434"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,7]]}},"alternative-id":["10.1177\/030089160008600434"],"URL":"https:\/\/doi.org\/10.1177\/030089160008600434","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,7]]}}}