{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:01:32Z","timestamp":1777917692064,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2001,1]]},"abstract":"<jats:p>\n                    Twenty patients with locally advanced cervical cancer (FIGO stage Ib-IIa \u201cbulky\u201d\/VIIb) were treated with three courses of weekly PVB (day 1: cisplatin, 50 mg\/m\n                    <jats:sup>2<\/jats:sup>\n                    ; vincristin, 1 mg\/m\n                    <jats:sup>2<\/jats:sup>\n                    ; bleomycin, 30 IU over 24-hr) in a neoadjuvant setting. Toxicity was generally mild (no grade 3-4 toxicity was observed), and the treatment was well tolerated without reduction of programmed dose intensity. Fourteen patients (70%) experienced a clinical response and underwent surgery within 20 days after the third course of chemotherapy. Six patients (30%) with stable disease were treated with salvage radiotherapy. Two of the 14 responders experienced a pathologic complete response (14.2%); microscopic disease was detected in one patient with clinical complete response. Pelvic node metastases were found in 4\/14 patients (28.5%) and microscopic parametrium involvement in 3\/14 (21.4%). All 14 patients had free margins of resection. A short-term weekly platinum-based chemotherapy is highly effective, has little toxicity, and allows a prompt salvage therapy for nonresponding patients.\n                  <\/jats:p>","DOI":"10.1177\/030089160108700106","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T05:31:15Z","timestamp":1523943075000},"page":"25-26","source":"Crossref","is-referenced-by-count":4,"title":["Short-Term Weekly Neoadjuvant Chemotherapy in the Treatment of Locally Advanced Cervical Cancer"],"prefix":"10.1177","volume":"87","author":[{"given":"Giampiero","family":"Porzio","sequence":"first","affiliation":[{"name":"Medical Oncology Unit, University of L'Aquila, L'Aquila, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Corrado","family":"Ficorella","sequence":"additional","affiliation":[{"name":"Medical Oncology Unit, University of L'Aquila, L'Aquila, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluigi","family":"Toro","sequence":"additional","affiliation":[{"name":"Medical Oncology Unit, University of L'Aquila, L'Aquila, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ida","family":"Paris","sequence":"additional","affiliation":[{"name":"Medical Oncology Unit, University of L'Aquila, L'Aquila, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrico","family":"Ricevuto","sequence":"additional","affiliation":[{"name":"Medical Oncology Unit, University of L'Aquila, L'Aquila, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Marchetti","sequence":"additional","affiliation":[{"name":"Medical Oncology Unit, University of L'Aquila, L'Aquila, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2001,1,1]]},"reference":[{"key":"bibr1-030089160108700106","first-page":"351","volume":"66","year":"1996","journal-title":"Gynecol Oncol"},{"key":"bibr2-030089160108700106","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-199605000-00022"},{"key":"bibr3-030089160108700106","first-page":"276","volume":"83","author":"Lhomme C.","year":"1996","journal-title":"Bull Cancer (Paris)"},{"key":"bibr4-030089160108700106","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008481228307"},{"key":"bibr5-030089160108700106","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(98)00404-3"},{"key":"bibr6-030089160108700106","first-page":"54","volume":"21","author":"Omura G","year":"1994","journal-title":"Semin Oncol"},{"key":"bibr7-030089160108700106","first-page":"173","volume":"18","author":"Giardina G.","year":"1997","journal-title":"Eur J Gynaecol Oncol"},{"key":"bibr8-030089160108700106","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8588(05)70165-9"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089160108700106","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089160108700106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:20:36Z","timestamp":1777659636000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030089160108700106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,1]]}},"alternative-id":["10.1177\/030089160108700106"],"URL":"https:\/\/doi.org\/10.1177\/030089160108700106","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,1]]}}}