{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:02:54Z","timestamp":1777917774795,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2002,5]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate the reliability of magnetic resonance imaging (MRI) performed with three-dimensional (3D) sequences in mammographically detected breast microcalcifications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>During an 8-month period, a group of 28 patients with mammographically detected microcalcifications suspicious for malignancy underwent MRI. Their ages ranged from 33 to 65 years. Examinations were performed with a 1.5 Tesla MR unit and a 3D T1 weighted sequence. Images were interpreted on the basis of morphologic parameters and dynamic behavior in the uptake of contrast medium (Gd-DTPA). Histologic findings were considered as the gold reference.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Histologic analysis revealed invasive carcinoma in 7 patients, 3 of which were associated with foci of lobular carcinoma in situ. Intraductal carcinoma was diagnosed in 8 patients, 1 of which was associated with a tubular carcinoma. Benign lesions accounted for 13 patients. All the neoplastic conditions showed enhancement on MR images (sensitivity, 100%), whereas early and intense enhancement was noted in 5 of 13 benign lesions (specificity, 61%). The positive predictive value was 75% and negative predictive value, 100%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although an overlap in the enhancement behavior of malignant and some benign lesions is clearly evident, a careful interpretation of MR images is helpful in detecting and mainly ruling out breast cancer combined with mammographically suspicious microcalcifications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/030089160208800308","type":"journal-article","created":{"date-parts":[[2018,4,23]],"date-time":"2018-04-23T11:37:19Z","timestamp":1524483439000},"page":"224-233","source":"Crossref","is-referenced-by-count":9,"title":["Breast Microcalcifications Studied with 3d Contrast-enhanced High-field Magnetic Resonance Imaging: More Accuracy in the Diagnosis of Breast Cancer"],"prefix":"10.1177","volume":"88","author":[{"given":"Giovanna","family":"Trecate","sequence":"first","affiliation":[{"name":"Unit of Diagnostic Radiology A, National Cancer Research, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John David","family":"Tesoro Tess","sequence":"additional","affiliation":[{"name":"Unit of Diagnostic Radiology A, National Cancer Research, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Vergnaghi","sequence":"additional","affiliation":[{"name":"Unit of Diagnostic Radiology A, National Cancer Research, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana","family":"Bergonzi","sequence":"additional","affiliation":[{"name":"Unit of Diagnostic Radiology C, National Cancer Research, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiziana","family":"De Simone","sequence":"additional","affiliation":[{"name":"Unit 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