{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:09:16Z","timestamp":1777918156423,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2009,3]]},"abstract":"<jats:p>Along with myasthenia, other paraneoplastic neurological syndromes (PNS) may occur in thymoma. Anti-Hu antibodies and a clinical \u201canti-Hu syndrome\u201d characterized by encephalitis and\/or painful neuropathies have been reported in only three patients at the time of the diagnosis of thymoma. We describe a severe anti-Hu-related autonomic neuropathy with gastrointestinal paresis and intestinal pseudo-obstruction with malabsorption that occurred concomitantly with the worsening of myasthenic symptoms long after the initial diagnosis of thymoma in a young patient. The clinical anti-Hu syndrome preceded the radiological diagnosis of thymoma recurrence. Treatment with plasma exchange led to a transient improvement of neurological symptoms.<\/jats:p>","DOI":"10.1177\/030089160909500219","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T04:03:29Z","timestamp":1519704209000},"page":"243-247","source":"Crossref","is-referenced-by-count":17,"title":["Thymoma Associated with Myasthenia and Autonomic anti-Hu Paraneoplastic Neuropathy"],"prefix":"10.1177","volume":"95","author":[{"given":"Matteo","family":"Simonelli","sequence":"first","affiliation":[{"name":"Department of Medical Oncology and Hematology, Istituto Clinico Humanitas, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe Luigi","family":"Banna","sequence":"additional","affiliation":[{"name":"Unit of Medical Oncology, Vittorio Emanuele II University Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando","family":"Santoro","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology and Hematology, Istituto Clinico Humanitas, Rozzano, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,1,29]]},"reference":[{"key":"bibr1-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra023009"},{"key":"bibr2-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.4.1146"},{"key":"bibr3-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1042\/cs1020475"},{"key":"bibr4-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1097\/01.wco.0000173462.17135.ee"},{"key":"bibr5-030089160909500219","first-page":"94","volume":"3","author":"Senties-Madrid H.","year":"2001","journal-title":"Isr Med Assoc J"},{"key":"bibr6-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1002\/neu.480250206"},{"key":"bibr7-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.3.652"},{"key":"bibr8-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/124.6.1138"},{"key":"bibr9-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2004.07.012"},{"key":"bibr10-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)74815-7"},{"key":"bibr11-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199203000-00001"},{"key":"bibr12-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf006"},{"key":"bibr13-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2004.07.009"},{"key":"bibr14-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1007\/s11938-005-0046-4"},{"key":"bibr15-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.59.6.929"},{"key":"bibr16-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-0172(98)80039-5"},{"key":"bibr17-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2006.10.003"},{"key":"bibr18-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.4.719"},{"key":"bibr19-030089160909500219","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-005-0001-7"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089160909500219","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089160909500219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:32:18Z","timestamp":1777660338000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030089160909500219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["10.1177\/030089160909500219"],"URL":"https:\/\/doi.org\/10.1177\/030089160909500219","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}