{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T18:29:20Z","timestamp":1778610560881,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:p>\n                    Sunitinib is an oral multitargeted tyrosine kinase inhibitor with antiangiogenic properties used for treatment of renal cell carcinoma and gastrointestinal stromal tumors at a dose of 50 mg\/day consecutively for 4 weeks followed by 2 weeks off per cycle. At present, no data are available on the early prediction of sunitinib response in renal cell carcinoma. We report a clinical case of a patient with metastatic renal cell carcinoma diagnosed with\n                    <jats:sup>11<\/jats:sup>\n                    C-acetate PET and conventional CT and treated with sunitinib. Partial and complete remission documented by CT was preceded by early functional tumor inhibition shown by\n                    <jats:sup>11<\/jats:sup>\n                    C-acetate-PET after only 14 days of therapy. This case report highlights some interesting points related to the potential role of a novel non-FDG PET tracer,\n                    <jats:sup>11<\/jats:sup>\n                    C-acetate, in the early prediction of the response to targeted therapies in metastatic renal cell carcinoma.\n                  <\/jats:p>","DOI":"10.1177\/030089160909500320","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T04:04:51Z","timestamp":1519704291000},"page":"382-384","source":"Crossref","is-referenced-by-count":30,"title":["<sup>11<\/sup>\n                    C-Acetate PET for Early Prediction of Sunitinib Response in Metastatic Renal Cell Carcinoma"],"prefix":"10.1177","volume":"95","author":[{"given":"Alessandra","family":"Maleddu","sequence":"first","affiliation":[{"name":"Institute of Hematology and Medical Oncology \u201cL.&A. 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