{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T02:56:52Z","timestamp":1788404212348,"version":"build-2803163510"},"reference-count":10,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2019,12]]},"abstract":"\n Background:<\/jats:title>\n Cytotoxic and immunosuppressive therapies for cancer treatment may allow hepatitis reactivation. Hepatitis due to viral hepatitis reactivation is detected in 14%\u201325% of hepatitis B surface antigen (HBsAg)\u2013positive cancer patients undergoing anticancer treatments. Drug toxicity may be confused with hepatitis reactivation, which may cause a delay in diagnosis.<\/jats:p>\n <\/jats:sec>\n \n Case report:<\/jats:title>\n A 60-year-old man with metastatic renal cell carcinoma was treated with sunitinib. Sixteen months after sunitinib inception, liver enzymes were elevated and viral hepatitis reactivation was detected as hepatitis delta virus infection in the HBsAg-positive patient.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Cancer patients should be screened for viral hepatitis prior to immunosuppressive therapy or chemotherapy.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/0300891619840279","type":"journal-article","created":{"date-parts":[[2019,4,2]],"date-time":"2019-04-02T00:32:26Z","timestamp":1554165146000},"page":"NP72-NP74","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Hepatitis D reactivation in a patient with metastatic renal cell carcinoma receiving sunitinib therapy"],"prefix":"10.1177","volume":"105","author":[{"given":"Emre","family":"Akar","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Bak\u0131rkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Faculty of Medicine, Bakirkoy, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet Haluk","family":"Y\u00fccel","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Bak\u0131rkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Faculty of Medicine, Bakirkoy, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tunahan","family":"\u015eahin","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Bak\u0131rkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Faculty of Medicine, Bakirkoy, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deniz","family":"Tural","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Bak\u0131rkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Faculty of Medicine, Bakirkoy, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,4,1]]},"reference":[{"key":"bibr1-0300891619840279","unstructured":"Centers for Disease Control and Prevention. 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