{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:14:31Z","timestamp":1777918471111,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T00:00:00Z","timestamp":1571616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>We assessed the frequency of triple-positive serology (viral capsid antigen [VCA]\u2013immunoglobulin G [IgG], VCA\u2013immunoglobulin M, Epstein-Barr nuclear antigen\u2013IgG) for Epstein-Barr virus (EBV) in a small number of patients with angioimmunoblastic T-cell lymphoma (AITL) at disease onset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Nine patients with newly diagnosed AITL were retrospectively enrolled in the present study. For all of them, EBV serology data were available.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of 9 patients, 7 (77.7%) had a triple-positive serology (VCA-IgG, VCA-IgM, EBNA-IgG ) for EBV. These patients were characterized by bone marrow involvement, high incidence of thrombocytopenia, and poor prognosis according to Revised International Prognostic Index and Prognostic Index for Angioimmunoblastic T-cell Lymphoma scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Assessment of both viremia and serology for EBV could be useful in patients with clinical and laboratory data suggesting lymphoma diagnosis; furthermore, although our data need to be validated in a larger cohort of patients, triple positivity for EBV serology might help to direct the diagnosis toward AITL.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300891619882504","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T14:49:25Z","timestamp":1571669365000},"page":"424-426","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Is triple-positive serology for Epstein-Barr virus (VCA-IgG, VCA-IgM, EBNA-IgG) a specific feature of angioimmunoblastic T-cell lymphoma?"],"prefix":"10.1177","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7581-5824","authenticated-orcid":false,"given":"Davide","family":"Facchinelli","sequence":"first","affiliation":[{"name":"Section of Hematology, Department of Medicine, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Parisi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Diagnostics, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Krampera","sequence":"additional","affiliation":[{"name":"Section of Hematology, Department of Medicine, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dino","family":"Veneri","sequence":"additional","affiliation":[{"name":"Section of Hematology, Department of Medicine, University of Verona and Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,10,21]]},"reference":[{"key":"bibr1-0300891619882504","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.37.3647"},{"key":"bibr2-0300891619882504","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-06-2508"},{"key":"bibr3-0300891619882504","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2009.08003.x"},{"key":"bibr4-0300891619882504","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2003.04335.x"},{"key":"bibr5-0300891619882504","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2007.06620.x"},{"key":"bibr6-0300891619882504","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2017.476"},{"key":"bibr7-0300891619882504","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2017.1300894"},{"key":"bibr8-0300891619882504","doi-asserted-by":"publisher","DOI":"10.5501\/wjv.v1.i1.31"},{"key":"bibr9-0300891619882504","doi-asserted-by":"publisher","DOI":"10.4081\/hr.2017.7088"},{"key":"bibr10-0300891619882504","first-page":"7","author":"Beer T","year":"2015","journal-title":"Hematol Rep"},{"key":"bibr11-0300891619882504","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2011.061507"},{"key":"bibr12-0300891619882504","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000002061"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300891619882504","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300891619882504","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300891619882504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:39:53Z","timestamp":1777660793000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300891619882504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,21]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1177\/0300891619882504"],"URL":"https:\/\/doi.org\/10.1177\/0300891619882504","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,21]]}}}