{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:15:07Z","timestamp":1777918507668,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T00:00:00Z","timestamp":1591574400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p>Coronavirus disease 2019 (COVID-19) hospital reorganization may result in reduced ability for the hospital to fully use its armamentarium for battling cancer. Thus different therapeutic modalities have been recommended. During the pandemic, despite regulatory agencies\u2019 recommendations, several considerations and doubts remain for oncologic clinical trials. Considering patients who had been enrolled before the pandemic, and who plan to take the study medication, the situation becomes complicated. These patients should undergo monitoring visits, blood sampling, questionnaire, physical examination, and drug and radiation administration. To avoid deviations from the protocol and trial discontinuation, follow-up should be performed regularly, in concordance with safety guidelines. Here we report several considerations.<\/jats:p>","DOI":"10.1177\/0300891620933672","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T08:02:54Z","timestamp":1591603374000},"page":"271-272","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Patients with cancer in the COVID-19 era: the clinical trial issue"],"prefix":"10.1177","volume":"106","author":[{"given":"Marcello","family":"Scarcia","sequence":"first","affiliation":[{"name":"Urology Department, General Regional Hospital F. Miulli, Acquaviva delle fonti (BA), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe Mario","family":"Ludovico","sequence":"additional","affiliation":[{"name":"Urology Department, General Regional Hospital F. Miulli, Acquaviva delle fonti (BA), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Fortunato","sequence":"additional","affiliation":[{"name":"Urology Department, General Regional Hospital F. Miulli, Acquaviva delle fonti (BA), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4201-5852","authenticated-orcid":false,"given":"Alba","family":"Fiorentino","sequence":"additional","affiliation":[{"name":"Radiation Oncology Department, General Regional Hospital F. Miulli, Acquaviva delle fonti (BA), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,6,8]]},"reference":[{"key":"bibr1-0300891620933672","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp2005492"},{"key":"bibr2-0300891620933672","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.04.002"},{"key":"bibr3-0300891620933672","doi-asserted-by":"publisher","DOI":"10.1016\/j.adro.2020.03.003"},{"key":"bibr4-0300891620933672","doi-asserted-by":"publisher","DOI":"10.1111\/bju.15061"},{"key":"bibr5-0300891620933672","doi-asserted-by":"publisher","DOI":"10.1177\/0300891620923790"},{"key":"bibr6-0300891620933672","unstructured":"Clinical trials\u2019 management in Italy during the COVID-19 (coronavirus disease 19) emergency, https:\/\/www.aifa.gov.it\/documents\/20142\/871583\/Comunicato_gestione_studi_clinici_in_emergenza_COVID-19_EN_12.03.2020.pdf\/ee1f33e3-bb3e-9ce9-2a93-b33e88eea94d (accessed 10 May 2020)."},{"key":"bibr7-0300891620933672","doi-asserted-by":"publisher","DOI":"10.1007\/s11547-018-0960-x"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300891620933672","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300891620933672","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300891620933672","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:40:41Z","timestamp":1777660841000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300891620933672"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,8]]},"references-count":7,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1177\/0300891620933672"],"URL":"https:\/\/doi.org\/10.1177\/0300891620933672","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,8]]}}}