{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:15:33Z","timestamp":1777918533585,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,12,16]],"date-time":"2020-12-16T00:00:00Z","timestamp":1608076800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>During 2020, medical clinical activities were dramatically modified by the coronavirus disease 2019 (COVID-19) emergency. We aim to evaluate the impact of COVID-19 on radiotherapy (RT) practice in a hub cancer center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective data collection of patients with suspected COVID-19 infection, identified by pathognomonic symptoms feedback at triage realized at the entrance to RT division. Inclusion criteria were diagnosis of oncologic disease, COVID-19\u2013related symptoms, and signed written informed consent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Between 1 March and 30 June 2020, 1,006 patients accessed our RT division for RT simulation or treatment. Forty-four patients matched inclusion criteria (4.4% of all patients): 29 women and 15 men. Seventeen patients had metastatic disease. Twenty-one patients reported fever, 6 presented dyspnea, 4 complained of ageusia and anosmia, and 3 developed conjunctivitis. Thirty-six patients underwent nasal swab, with 7 positive results. From our cohort, 4 cases of pneumonia were diagnosed with computed tomography scan imaging: 3 were related to COVID-19 infection, while the fourth was evaluated as an RT adverse event. From the entire series, 4 patients died: 3 during hospitalization in intensive care unit of complications of COVID-19 and 1 of other causes neither COVID-19 nor cancer-related.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Cancer hub allows for safe RT practice continuation while minimizing the spread of contagion in this frail patient population. A challenge for the future will be to understand pandemic consequences in cancer natural history and manage its clinical impact.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0300891620980065","type":"journal-article","created":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T01:45:24Z","timestamp":1608169524000},"page":"498-503","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["COVID-19 impact in radiotherapy practice in an oncology hub: a screenshot from Lombardy, Italy"],"prefix":"10.1177","volume":"107","author":[{"given":"Giulia","family":"Corrao","sequence":"first","affiliation":[{"name":"Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy"},{"name":"Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Bergamaschi","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy"},{"name":"Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4655-4634","authenticated-orcid":false,"given":"Mattia","family":"Zaffaroni","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Sarra Fiore","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giammaria","family":"Bufi","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Cristina","family":"Leonardi","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Lazzari","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Alterio","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Cattani","sequence":"additional","affiliation":[{"name":"Medical Physics Unit, IEO, European Institute of Oncology IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Pravettoni","sequence":"additional","affiliation":[{"name":"Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy"},{"name":"Applied Research Division for Cognitive and Psychological Science, European Institute of Oncology IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabrizio","family":"Mastrilli","sequence":"additional","affiliation":[{"name":"Medical Administration, CMO, IEO, European Institute of Oncology IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Orecchia","sequence":"additional","affiliation":[{"name":"Scientific Direction, IEO, European Institute of Oncology, IRCCS, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Marvaso","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy"},{"name":"Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara Alicja","family":"Jereczek-Fossa","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy"},{"name":"Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,12,16]]},"reference":[{"key":"bibr1-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30240-0"},{"key":"bibr2-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2020.04.007"},{"key":"bibr3-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30096-6"},{"key":"bibr4-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30150-9"},{"key":"bibr5-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.06.007"},{"key":"bibr6-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1177\/0300891618784800"},{"key":"bibr7-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1002\/hed.26319"},{"key":"bibr8-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.03.029"},{"key":"bibr9-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.adro.2020.03.010"},{"key":"bibr10-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1186\/s13014-020-01527-1"},{"key":"bibr11-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2020.03.006"},{"key":"bibr12-0300891620980065","first-page":"618","volume":"107","author":"Thomson DJ","year":"2020","journal-title":"Radiother Oncol"},{"key":"bibr13-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020006028"},{"key":"bibr14-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2020-0267"},{"key":"bibr15-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1136\/esmoopen-2020-000779"},{"key":"bibr16-0300891620980065","unstructured":"World Health Organization, https:\/\/www.who.int\/ (accessed 21 September 2020)."},{"key":"bibr17-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.04.061"},{"key":"bibr18-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2020.03.006"},{"key":"bibr19-0300891620980065","first-page":"1","volume":"5","author":"ESMO","year":"2020","journal-title":"ESMO Open"},{"key":"bibr20-0300891620980065","first-page":"5","author":"Catanese S","year":"2020","journal-title":"ESMO Open"},{"key":"bibr21-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.04.010"},{"key":"bibr22-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.04.001"},{"key":"bibr23-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1038\/s41391-020-0258-7"},{"key":"bibr24-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-020-00454-4"},{"key":"bibr25-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2020.05.029"},{"key":"bibr26-0300891620980065","first-page":"5","author":"Passaro A","year":"2020","journal-title":"ESMO Open"},{"key":"bibr27-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.04.034"},{"key":"bibr28-0300891620980065","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.radonc.2020.04.040","volume":"149","author":"Vavassori A","year":"2020","journal-title":"Radiother Oncol"},{"key":"bibr29-0300891620980065","unstructured":"Rischio infettivo da coronavirus COVID 19: indicazioni per l\u2019oncologia da parte del Presidente AIOM, del Presidente eletto AIOM, del Presidente CIPOMO e del Presidente COMU, https:\/\/www.aiom.it\/wp-content\/uploads\/2020\/03\/20200313_COVID-19_indicazioni_AIOM-CIPOMO-COMU.pdf (accessed 21 September 2020)."},{"key":"bibr30-0300891620980065","unstructured":"Associazione Italiana di Radioterapia e Oncologia Clinica (AIRO) documento di indirizzo per la valutazione e la gestione del rischio dei pazienti e degli operatori nei reparti di radioterapia oncologica in corso di diffusione del COVID-19, https:\/\/www.radioterapiaitalia.it\/evento\/emergenza-covid-19 (accessed 21 September 2020)."},{"key":"bibr31-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000004083"},{"key":"bibr32-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000004489"},{"key":"bibr33-0300891620980065","doi-asserted-by":"publisher","DOI":"10.1177\/0300891620962197"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300891620980065","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300891620980065","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300891620980065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:41:18Z","timestamp":1777660878000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300891620980065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,16]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1177\/0300891620980065"],"URL":"https:\/\/doi.org\/10.1177\/0300891620980065","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,16]]}}}