{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:16:09Z","timestamp":1777918569137,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T00:00:00Z","timestamp":1644278400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100009647","name":"ministry of health","doi-asserted-by":"publisher","award":["Ricerca Corrente, Linea 2"],"award-info":[{"award-number":["Ricerca Corrente, Linea 2"]}],"id":[{"id":"10.13039\/100009647","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>This study assesses the risk of infection and clinical outcomes in a large consecutive population of cancer and non-cancer patients tested for SARS-CoV-2 status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Study patients underwent SARS-CoV-2 molecular-testing between 22 February 2020 and 31 July 2020, and were found infected (CoV2+ ve) or uninfected. History of malignancy was obtained from regional population-based cancer registries. Cancer-patients were distinguished by time between cancer diagnosis and SARS-CoV-2 testing (&lt;12\/\u2a7e12 months). Comorbidities, hospitalization, and death at 15 September 2020 were retrieved from regional population-based databases. The impact of cancer history on SARS-CoV-2 infection and clinical outcomes was calculated by fitting a multivariable logistic regression model, adjusting for sex, age, and comorbidities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among 552,362 individuals tested for SARS-CoV-2, 55,206 (10.0%) were cancer-patients and 22,564 (4.1%) tested CoV2+ ve. Irrespective of time since cancer diagnosis, SARS-CoV-2 infection was significantly lower among cancer patients (1,787; 3.2%) than non-cancer individuals (20,777; 4.2% - Odds Ratio (OR)=0.60; 0.57-0.63). CoV2+ ve cancer-patients were older than non-cancer individuals (median age: 77 versus 57 years; p&lt;0.0001), were more frequently men and with comorbidities. Hospitalizations (39.9% versus 22.5%; OR=1.61; 1.44-1.80) and deaths (24.3% versus 9.7%; OR=1.51; 1.32-1.72) were more frequent in cancer-patients. CoV2+ ve cancer-patients were at higher risk of death (lung OR=2.90; 1.58-5.24, blood OR=2.73; 1.88-3.93, breast OR=1.77; 1.32-2.35).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The risks of hospitalization and death are significantly higher in CoV2+ ve individuals with past or present cancer (particularly malignancies of the lung, hematologic or breast) than in those with no history of cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03008916211073771","type":"journal-article","created":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T03:11:16Z","timestamp":1644289876000},"page":"38-46","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Outcomes of SARS-CoV-2 infection in cancer versus non-cancer-patients: a population-based study in northeastern Italy"],"prefix":"10.1177","volume":"109","author":[{"given":"Massimo","family":"Rugge","sequence":"first","affiliation":[{"name":"Department of Medicine - DIMED, Surgical Pathology and Cytopathology Unit, Universit\u00e0 degli Studi di Padova, Padova, Italy"},{"name":"Veneto Tumour Registry, Azienda Zero, Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6025-5214","authenticated-orcid":false,"given":"Manuel","family":"Zorzi","sequence":"additional","affiliation":[{"name":"Veneto Tumour Registry, Azienda Zero, Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Guzzinati","sequence":"additional","affiliation":[{"name":"Veneto Tumour Registry, Azienda Zero, Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Stocco","sequence":"additional","affiliation":[{"name":"Veneto Tumour Registry, Azienda Zero, Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Avossa","sequence":"additional","affiliation":[{"name":"Regional Epidemiological Service Unit, Azienda Zero, Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5738-4584","authenticated-orcid":false,"given":"Stefania","family":"Del Zotto","sequence":"additional","affiliation":[{"name":"Friuli Venezia Giulia Regional Health Coordination Agency, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Clagnan","sequence":"additional","affiliation":[{"name":"Friuli Venezia Giulia Regional Health Coordination Agency, Udine, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludovica","family":"Bricca","sequence":"additional","affiliation":[{"name":"Department of Medicine - DIMED, Surgical Pathology and Cytopathology Unit, Universit\u00e0 degli Studi di Padova, Padova, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0565-8920","authenticated-orcid":false,"given":"Luigino","family":"Dal Maso","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology Unit, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Serraino","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology Unit, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,2,8]]},"reference":[{"key":"bibr1-03008916211073771","unstructured":"World Health Organization. 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