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Perineural infiltration represents one of the most important adverse prognostic factors and may impact negatively patient outcomes. While guidelines exist for defining radiotherapy treatment volumes in patients with cutaneous squamous cell carcinoma and clinical perineural infiltration, there is a notable gap in the literature regarding recommendations for cases with incidental perineural infiltration and parotid involvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A case of cutaneous squamous cell carcinoma of the auricular zone was proposed to an expert radiation oncologist panel.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The main issues concerned the inclusion of the surgical bed alone or the extension to the adjacent zone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This paper aims to provide a review of literature data and to propose a comprehensive approach to target volume definition in this setting of patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03008916251334879","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T01:00:36Z","timestamp":1746406836000},"page":"210-218","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Perineural invasion and parotid involvement in auricular cutaneous SCC: Which volumes to treat in postoperative radiotherapy?"],"prefix":"10.1177","volume":"111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1381-7012","authenticated-orcid":false,"given":"Paola","family":"Critelli","sequence":"first","affiliation":[{"name":"Radiation Oncology Department, Santa Croce and Carle Hospital, Cuneo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana","family":"Parisi","sequence":"additional","affiliation":[{"name":"Dipartimento di scienze Biomediche, odontoiatriche e delle immagini morfologiche e funzionali - Universit\u00e0 degli studi di Messina - AOU G. Martino di Messina, Messina, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Alterio","sequence":"additional","affiliation":[{"name":"Radiotherapy Division, European Institute of Oncology, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Scricciolo","sequence":"additional","affiliation":[{"name":"Dipartimento di radioterapia oncologica, Ospedale dell'Angelo, Venezia \u2013 Mestre, Mestre, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Maddalo","sequence":"additional","affiliation":[{"name":"Radiation Oncology Unit, Department of Medical and Surgical Specialties, Radiological Science and Public Health, ASST Spedali Civili of Brescia, University of Brescia, Brescia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8999-5208","authenticated-orcid":false,"given":"Pierluigi","family":"Bonomo","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4742-7672","authenticated-orcid":false,"given":"Domenico","family":"Romanello","sequence":"additional","affiliation":[{"name":"MedAustron Ion Therapy Center, Wiener Neustadt, Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Ronchi","sequence":"additional","affiliation":[{"name":"Radiation Oncology Unit, Clinical Department, National Center for Oncological Hadrontherapy (CNAO), Pavia, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Sibio","sequence":"additional","affiliation":[{"name":"S.C. 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