{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:18:08Z","timestamp":1777918688667,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T00:00:00Z","timestamp":1769212800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T00:00:00Z","timestamp":1769212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>\n                    Medical decision analysis is a method to make rational clinical decisions under uncertainty, enabling a mathematical combination of\n                    <jats:italic toggle=\"yes\">probabilities<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">utilities<\/jats:italic>\n                    (i.e. values assigned to outcomes under risk). Decision analysis is commonly used in health economics, but it is underexploited in the clinic. With a view to fostering the use of medical decision analysis at the cancer patient bedside, this paper provides basic templates for some typical clinical decisions in cancer treatment, namely affecting: the quantity\/quality of life trade-offs in curable cancer; adjuvant\/neoadjuvant treatments; cytoreductive treatments; active surveillance \/ watchful waiting choices; treatment of advanced cancer; cancer follow-up. The clinical use of medical decision analysis is challenged by several difficulties, which are briefly recalled. Contrary to clinical research, medical decision analysis does not build new evidence: it simply provides physicians with a method to personalize clinical decisions on the basis of available evidence. Its added value in clinical practice correlates with the complexity of a decision. However, it also has a great potential in medical education, in order to empower clinicians with skills improving their ability to rationally shape medical decisions and share them properly with their patients.\n                  <\/jats:p>","DOI":"10.1177\/03008916251404283","type":"journal-article","created":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T09:48:56Z","timestamp":1769248136000},"page":"11-21","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Medical decision analysis for personalized oncology at the patient bedside"],"prefix":"10.1177","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4056-8023","authenticated-orcid":false,"given":"Paolo G.","family":"Casali","sequence":"first","affiliation":[{"name":"Department of Oncology and Hemato-oncology, University of Milan, Italy"},{"name":"Mesenchymal and Rare Cancer Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Licitra","sequence":"additional","affiliation":[{"name":"Department of Oncology and Hemato-oncology, University of Milan, Italy"},{"name":"Head and Neck Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0425-4692","authenticated-orcid":false,"given":"Salvatore","family":"Provenzano","sequence":"additional","affiliation":[{"name":"Mesenchymal and Rare Cancer Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilaria","family":"Pellegrini","sequence":"additional","affiliation":[{"name":"Academic Medical Oncology Unit, IRCCS Ospedale Policlinico San Martino, Genova, 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