{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T13:36:16Z","timestamp":1787578576546,"version":"build-2736575974"},"reference-count":32,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Southeast Regional Research Delivery Network"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Tumori"],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Optimal postoperative follow-up for lung neuroendocrine tumours (L-NET) and surgical resection approaches remain debated. This audit aimed to benchmark long-term outcomes after L-NET surgery at a high-volume centre, identify prognostic factors, and estimate follow-up duration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a retrospective audit of 633 L-NET resections at a high-volume centre (1997\u20132023). Kaplan-Meier plots for overall survival (OS) were generated. Cox regression was used to identify the factors affecting OS. Expected survival was generated by matching age, sex, and year of surgery to national life tables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Median age was 63 years; 66.8% were female; 78.2% had typical morphology; 78.2% were stage 1; and lobectomy predominated (83.7%). Ten-year OS was 80.4% for all cases and 82.7%, 84.5%, 58.9%, and 67.0% for lobectomy, pneumonectomy, segmentectomy, and wedge resection, respectively. Actual OS overlapped at ~220 months for all cases. Multivariable analysis showed that worse all-cause mortality was associated with advanced age (aHR 1.08) and lymphovascular invasion (aHR 2.38), but not procedure type.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>This audit provides valuable insights into the benefits and risks of surgery for L-NET at our centre. It identifies risk factors for increased all-cause mortality. It provides data on follow-up, which can inform local case selection, guidelines and policies at our centre.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/03008916261472659","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T04:09:52Z","timestamp":1787198992000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Survival of carcinoid lung neuroendocrine tumours after surgical resection: A retrospective audit of 633 cases over 26 years"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2694-2763","authenticated-orcid":false,"given":"Mohamed","family":"Mortagy","sequence":"first","affiliation":[{"name":"Hampshire Hospitals NHS Foundation Trust, Basingstoke, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6779-5589","authenticated-orcid":false,"given":"Ker Shiong","family":"Tan","sequence":"additional","affiliation":[{"name":"Hampshire Hospitals NHS Foundation Trust, Basingstoke, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Line","family":"El Asmar","sequence":"additional","affiliation":[{"name":"Hampshire Hospitals NHS Foundation Trust, Basingstoke, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Nonaka","sequence":"additional","affiliation":[{"name":"Cellular Pathology, Guy\u2019s and St. Thomas NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saoirse","family":"Dolly","sequence":"additional","affiliation":[{"name":"Kings Health Partners ENETS Centre of Excellence, King\u2019s College NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajaventhan","family":"Srirajaskanthan","sequence":"additional","affiliation":[{"name":"Kings Health Partners ENETS Centre of Excellence, King\u2019s College NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Clement","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Maastricht University Medical Center, Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Bille","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Unit, Guy\u2019s and St Thomas NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliet","family":"King","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Unit, Guy\u2019s and St Thomas NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akshay","family":"Patel","sequence":"additional","affiliation":[{"name":"Thoracic Surgery Unit, Guy\u2019s and St Thomas NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4824-6600","authenticated-orcid":false,"given":"John","family":"Ramage","sequence":"additional","affiliation":[{"name":"Hampshire Hospitals NHS Foundation Trust, Basingstoke, UK"},{"name":"Kings Health Partners ENETS Centre of Excellence, King\u2019s College NHS Foundation Trust, London, UK"},{"name":"University of Winchester, Winchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13081753"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15061695"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v16.i5.106630"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2017.01.59"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0000000000000630"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1530\/EC-23-0331"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2020.01.07"},{"key":"e_1_3_2_9_2","first-page":"335","article-title":"Prognostic factors in typical and atypical pulmonary carcinoids","volume":"17","author":"Ramirez RA","year":"2017","unstructured":"Ramirez RA, Beyer DT, Diebold AE, et al. 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