{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:02:13Z","timestamp":1777917733816,"version":"3.51.4"},"reference-count":4,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1961,1,1]],"date-time":"1961-01-01T00:00:00Z","timestamp":-283996800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[1961,1]]},"abstract":"<jats:p>Two lots, of 20 female rats each, were inoculated with 10 mg of 3,4-benzpyrene and submitted, one month later, to a Vitamin A-deficient diet. One of the lots was then subjected to periodic skin depilation in the site of tumour occurrence as well as in the contralateral side.<\/jats:p>\n                  <jats:p>In the vitamin-deficient and depilated animals, a considerable hair reduction and hypoplasia was observed in the skin overlying the tumour, whereas such phenomenon appeared to be moderate in the animals only submitted to the Vitamin A-deficient diet. In all animals a hypoplasia of the sebaceous glands was observed, especially above the tumour. An epidermal hyperkeratosis was demonstrated in vitamin-deficient and depilated animals as well as in only vitamin-deficient ones, mainly at the tumour level.<\/jats:p>","DOI":"10.1177\/030089166104700101","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:25:12Z","timestamp":1523881512000},"page":"1-12","source":"Crossref","is-referenced-by-count":0,"title":["Iperplasia Collaterale Nella Oncogenesi Sperimentale Del Ratto: 1. - Rilievi in corso di avitaminosi a combinata a depilazione"],"prefix":"10.1177","volume":"47","author":[{"given":"V.","family":"Carminati","sequence":"first","affiliation":[{"name":"dall'Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Divisione Biologica Sperimentale, diretta dal prof. V. Carminati"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Baglioni","sequence":"additional","affiliation":[{"name":"dall'Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Divisione Biologica Sperimentale, diretta dal prof. V. Carminati"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1961,1,1]]},"reference":[{"key":"bibr1-030089166104700101","doi-asserted-by":"publisher","DOI":"10.1177\/030089165504100601"},{"key":"bibr2-030089166104700101","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1953.119"},{"key":"bibr3-030089166104700101","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1955.58"},{"key":"bibr4-030089166104700101","unstructured":"MontagnaW. The structure and function of skin. Academic Press Inc. New York, 1956, pag. 244."}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089166104700101","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089166104700101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:21:41Z","timestamp":1777659701000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030089166104700101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1961,1]]},"references-count":4,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1961,1]]}},"alternative-id":["10.1177\/030089166104700101"],"URL":"https:\/\/doi.org\/10.1177\/030089166104700101","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[1961,1]]}}}