{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:08:53Z","timestamp":1777918133814,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1982,6,1]],"date-time":"1982-06-01T00:00:00Z","timestamp":391737600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[1982,6]]},"abstract":"<jats:p>From February 1981 to September 1981, 16 patients (19 fields) with histologically proven malignancy (10 squamous carcinoma, 4 melanoma, 1 adenocarcinoma, 1 chordoma) were treated with hyperthermia combined with radiotherapy or chemotherapy (1 patient). There were 5 females and 11 males; average age was 65 years, range 45 to 94 years; 15 patients had a Karnofsky index greater than 50%. Hyperthermia (42.5 44.0 \u00b0C) was induced by 250 MHz to 1 GHz microwaves (BSD - 1000 Unit). Thermometry was performed by means of non-perturbing probes placed in intratumorally inserted catheters and by measurement of skin temperatures. After hyperthermia plus radiotherapy (18 fields), 9 patients showed 100% response, 5 a volume regression of more than 50%, 3 less than 50% and 1 no change. After chemotherapy plus hyperthermia, 1 patient showed no change. No significant side effects were observed (3 skin burns in 147 hyperthermia treatment sessions).<\/jats:p>","DOI":"10.1177\/030089168206800309","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:25:36Z","timestamp":1523881536000},"page":"247-251","source":"Crossref","is-referenced-by-count":4,"title":["Local Microwave Hyperthermia in Cancer Therapy. Preliminary Report"],"prefix":"10.1177","volume":"68","author":[{"given":"Riccardo","family":"Valdagni","sequence":"first","affiliation":[{"name":"Centro Oncologico, Istituti Ospedalieri, Trento"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Amichetti","sequence":"additional","affiliation":[{"name":"Centro Oncologico, Istituti Ospedalieri, Trento"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Dell'Orsola","sequence":"additional","affiliation":[{"name":"Centro Oncologico, Istituti Ospedalieri, Trento"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1982,6,1]]},"reference":[{"key":"bibr1-030089168206800309","doi-asserted-by":"publisher","DOI":"10.1177\/030089167906500409"},{"key":"bibr2-030089168206800309","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(80)90029-2"},{"key":"bibr3-030089168206800309","first-page":"257","volume-title":"In: Hyperthermia in Radiation Oncology","author":"Arcangeli G.","year":"1980"},{"key":"bibr4-030089168206800309","first-page":"527","volume":"17","author":"Bender E.","year":"1966","journal-title":"Acta Biol. 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Phys."},{"key":"bibr16-030089168206800309","first-page":"771","volume":"15","author":"Muckle D.S.","year":"1978","journal-title":"Br. J. Cancer"},{"key":"bibr17-030089168206800309","first-page":"61","volume":"66","author":"Nielsen O.","year":"1981","journal-title":"J. Natl. Cancer Inst."},{"key":"bibr18-030089168206800309","volume-title":"Effect of environmental factors.","author":"Nielsen O.S.","year":"1980"},{"key":"bibr19-030089168206800309","author":"Roizin-Towle E.","year":"1980","journal-title":"The interaction of hyperthermia and cytotoxic agents."},{"key":"bibr20-030089168206800309","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-81080-0"},{"key":"bibr21-030089168206800309","author":"Schrader U.","year":"1980","journal-title":"Hyperthermia: dependence on radiation quality and dose rate."},{"key":"bibr22-030089168206800309","author":"Van Beuningen D.","year":"1980","journal-title":"Proliferation kinetics of human melanoma cells after fractioned hyperthermia and irradiation."},{"key":"bibr23-030089168206800309","first-page":"467","volume":"19","author":"Westra A.","year":"1971","journal-title":"Int. J. Radiat. 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