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Eight patients (6 men and 2 women) were evaluated for clinical response and 9 for toxicity. No complete regression was observed, and partial regression was obtained only in 3 patients (37.5 %). Severe leukopenia and thrombocytopenia occurred only occasionally; moderate nausea and vomiting were observed in 5 cases. Nephrotoxicity was noted in 4 of the 9 patients evaluable for toxicity, and 2 of them, with ureteral obstruction, died of renal failure.\n                  <\/jats:p>","DOI":"10.1177\/030089168407000114","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T05:32:19Z","timestamp":1523943139000},"page":"85-88","source":"Crossref","is-referenced-by-count":7,"title":["Cis-Diamminedichloroplatinum Activity in Bidimensionally Measurable Metastatic Lesions of Bladder Carcinoma"],"prefix":"10.1177","volume":"70","author":[{"given":"Mario","family":"De Lena","sequence":"first","affiliation":[{"name":"Ospedale Provinciale Specializzato in Oncologia, Bari"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vito","family":"Lorusso","sequence":"additional","affiliation":[{"name":"Ospedale Provinciale Specializzato in Oncologia, Bari"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrico","family":"Iacobellis","sequence":"additional","affiliation":[{"name":"Ospedale Regionale Consorziale, Bari"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franco","family":"Marzullo","sequence":"additional","affiliation":[{"name":"Ospedale Provinciale Specializzato in Oncologia, Bari"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evaristo","family":"Maiello","sequence":"additional","affiliation":[{"name":"Ospedale Provinciale Specializzato in Oncologia, Bari"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Cramarossa","sequence":"additional","affiliation":[{"name":"Ospedale Provinciale Specializzato in Oncologia, Bari"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1984,2,1]]},"reference":[{"key":"bibr1-030089168407000114","first-page":"461","volume":"22","author":"Einstein A.","year":"1981","journal-title":"A national bladder cancer collaborative group. 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