{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:51:23Z","timestamp":1791978683445,"version":"4.4.0"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1985,8,1]],"date-time":"1985-08-01T00:00:00Z","timestamp":491702400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[1985,8]]},"abstract":"<jats:p>The role in tumor spread and the prognostic value of metastasis in a prelaryngeal node were investigated in 124 cases of laryngeal and hypopharyngeal carcinoma selected from about 900 total laryngectomies and pharyngolaryngectomies. Metastasis in a prelaryngeal node was noted in 26 cases: 22 without capsular rupture (N+) and 4 with capsular rupture (N+R+). Vascular embolism (E+) was never noted. Patients with a metastatic prelaryngeal node had a tumor of the piriform sinus in 13 cases (50 %), a transglottic tumor in 6, glotto-subglottic in 3, glottic in 2 and supraglottic in 2. They also more frequently had involvement of the cervical nodes (81 %) and of the thyroid gland. The 5-year survival in these patients is very poor: only 3 patients (11.5 %) were alive and free of disease. These data demonstrate the role of prelaryngeal nodes in tumors that affect the hypopharynx and the antero-inferior portion of the larynx and that directly reach this node through the anterior lymphatic peduncle.<\/jats:p>","DOI":"10.1177\/030089168507100407","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:16:16Z","timestamp":1523880976000},"page":"361-365","source":"Crossref","is-referenced-by-count":32,"title":["Prognostic Value of the Prelaryngeal Node in Laryngeal and Hypopharyngeal Carcinoma"],"prefix":"10.1177","volume":"71","author":[{"given":"Leonardo","family":"Resta","sequence":"first","affiliation":[{"name":"Istituto di Anatomia e Istologia Patologica, Universit\u00e0 degli Studi di Bari, Italia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Micheau","sequence":"additional","affiliation":[{"name":"Departement d'Anatomie Pathologique (Histopatologie A), Institut Gustave-Roussy, Villejuif, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonietta","family":"Cimmino","sequence":"additional","affiliation":[{"name":"Istituto di Anatomia e Istologia Patologica, Universit\u00e0 degli Studi di Bari, Italia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1985,8,1]]},"reference":[{"key":"bibr1-030089168507100407","first-page":"595","volume":"8","author":"Agazzi C.","year":"1968","journal-title":"Rev. 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