{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:10:48Z","timestamp":1777918248247,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[1985,12,1]],"date-time":"1985-12-01T00:00:00Z","timestamp":502243200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[1985,12]]},"abstract":"<jats:p>\n                    Peripheral T lymphocytes from 31 patients with monoclonal gammopathy of undetermined significance (MGUS), and from a group of controls of the same age range, were stained using monoclonal antibodies of the OKT series. The absolute number and the percentage of OKT3\n                    <jats:sup>+<\/jats:sup>\n                    cells did not differ in patients compared with the controls. The percentage and absolute number of T-cell subsets with helper\/inducer OKT4\n                    <jats:sup>+<\/jats:sup>\n                    and suppressor\/cytotoxic OKT8\n                    <jats:sup>+<\/jats:sup>\n                    phenotype were not different from those of the controls, thus the OKT4\/OKT8 ratio in the patients with MGUS was normal (1.60 versus 1.57 in normal controls). These results suggest that MGUS is a B-cell disorder without imbalance of peripheral T-cell subsets unlike B-cell malignancies such as multiple myeloma and B-cell chronic lymphocytic leukemia.\n                  <\/jats:p>","DOI":"10.1177\/030089168507100605","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:25:23Z","timestamp":1523881523000},"page":"543-546","source":"Crossref","is-referenced-by-count":1,"title":["T-cell Subsets Defined by Monoclonal Antibodies in Monoclonal Gammopathy of Undetermined Significance (Mgus)"],"prefix":"10.1177","volume":"71","author":[{"given":"Luigi","family":"Cavanna","sequence":"first","affiliation":[{"name":"1a Divisione Medica, Ospedale di Piacenza"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Di Stasi","sequence":"additional","affiliation":[{"name":"1a Divisione Medica, Ospedale di Piacenza"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Fornari","sequence":"additional","affiliation":[{"name":"1a Divisione Medica, Ospedale di Piacenza"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Civardi","sequence":"additional","affiliation":[{"name":"1a Divisione Medica, Ospedale di Piacenza"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franco","family":"Binelli","sequence":"additional","affiliation":[{"name":"1a Divisione Medica, Ospedale di Piacenza"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta","family":"Buscarmi","sequence":"additional","affiliation":[{"name":"1a Divisione Medica, Ospedale di Piacenza"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Buscarmi","sequence":"additional","affiliation":[{"name":"1a Divisione Medica, Ospedale di Piacenza"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1985,12,1]]},"reference":[{"key":"bibr1-030089168507100605","doi-asserted-by":"publisher","DOI":"10.1007\/BF00200046"},{"key":"bibr2-030089168507100605","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1981.tb02682.x"},{"key":"bibr3-030089168507100605","first-page":"59","author":"Cavanna L.","year":"1984","journal-title":"Abstract Int. 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