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In a nation-wide collection of cases in Italy, 15 children (0\u201314 years of age) with NF and cancer or leukemia were identified; 13 of them had been diagnosed with cancer between 1976\u201383. The expected number of children with cancer and NF in 1976\u201383 was 4.48. The distribution of tumor types was different from that found in the general population, with a higher proportion of tumors of neural crest origin as well as soft tissue sarcomas. In 7\/15 the family history was positive for NF; in 5\/7 the individuals affected included the mother and\/or a maternal relative.<\/jats:p>","DOI":"10.1177\/030089168707300301","type":"journal-article","created":{"date-parts":[[2018,4,17]],"date-time":"2018-04-17T05:34:59Z","timestamp":1523943299000},"page":"209-212","source":"Crossref","is-referenced-by-count":6,"title":["Neurofibromatosis and Malignant Childhood Cancers: A Survey in Italy, 1970\u201383"],"prefix":"10.1177","volume":"73","author":[{"given":"Maria Luisa","family":"Mosso","sequence":"first","affiliation":[{"name":"Servizio di Epidemiologia dei Tumori, Universit\u00e0 di Torino"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Castello","sequence":"additional","affiliation":[{"name":"Cliniche Pediatriche delle Universit\u00e0 degli Studi di Roma"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franca Fossati","family":"Bellani","sequence":"additional","affiliation":[{"name":"Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Teresa","family":"Di Tullio","sequence":"additional","affiliation":[{"name":"Cliniche Pediatriche delle Universit\u00e0 degli Studi di Roma, Napoli"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franco","family":"Loiacono","sequence":"additional","affiliation":[{"name":"Cliniche Pediatriche delle Universit\u00e0 degli Studi di Roma, Bari"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Paolucci","sequence":"additional","affiliation":[{"name":"Cliniche Pediatriche delle Universit\u00e0 degli Studi di Roma, Bologna"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Tamaro","sequence":"additional","affiliation":[{"name":"Cliniche Pediatriche delle Universit\u00e0 degli Studi di Roma, Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedetto","family":"Terracini","sequence":"additional","affiliation":[{"name":"Servizio di Epidemiologia dei Tumori, Universit\u00e0 di Torino"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Pastore","sequence":"additional","affiliation":[{"name":"Servizio di Epidemiologia dei Tumori, Universit\u00e0 di Torino"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1987,6,1]]},"reference":[{"key":"bibr1-030089168707300301","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80362-X"},{"key":"bibr2-030089168707300301","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)90868-7"},{"key":"bibr3-030089168707300301","first-page":"97A","volume":"32","author":"Bader J.L.","year":"1980","journal-title":"Am. 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