{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:12:19Z","timestamp":1777918339896,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1988,2,1]],"date-time":"1988-02-01T00:00:00Z","timestamp":570672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[1988,2]]},"abstract":"<jats:p>Between 1976 and 1985, at the Obstetrics and Gynecology Department of Milan University, a total of 309 cases of hydatidiform mole, 223 complete moles and 86 partial moles, were monitored with the assay of beta-human chorionic gonadotropin, following a postmolar biochemical surveillance program. Spontaneous remission of the disease occurred in 287 (92.9%) patients. Marker levels were undetectable in 80.4 % of cases within 60 days after evacuation of the mole and in 19.6% between 61 and 140 days. There were 22 (7.1%) patients diagnosed as having gestational trophoblastic tumors (GTT) and treated with chemotherapy: 20 were complete moles and 2 partial moles. Considering these data, the authors suggest different follow-up times for partial and complete moles and confirm the necessity of selection criteria in a diagnosis of GTT.<\/jats:p>","DOI":"10.1177\/030089168807400116","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:16:01Z","timestamp":1523880961000},"page":"93-96","source":"Crossref","is-referenced-by-count":6,"title":["Analysis of 309 Cases after Hydatidiform Mole: Different Follow-Up Program According to Biologic Behavior"],"prefix":"10.1177","volume":"74","author":[{"given":"Giorgio","family":"Bolis","sequence":"first","affiliation":[{"name":"III Clinica Ostetrica e Ginecologica, Universit\u00e0 di Milano"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Belloni","sequence":"additional","affiliation":[{"name":"IV Clinica Ostetrica e Ginecologica, Universit\u00e0 di Milano"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Bonazzi","sequence":"additional","affiliation":[{"name":"V Clinica Ostetrica e Ginecologica, Settore Didattico di Monza, Universit\u00e0 di Milano"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgia","family":"Mangili","sequence":"additional","affiliation":[{"name":"I Clinica Ostetrica e Ginecologica, Universit\u00e0 di Milano"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Presti","sequence":"additional","affiliation":[{"name":"III Clinica Ostetrica e Ginecologica, Universit\u00e0 di Milano"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flavia","family":"Zanaboni","sequence":"additional","affiliation":[{"name":"III Clinica Ostetrica e Ginecologica, Universit\u00e0 di Milano"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Costantino","family":"Mangioni","sequence":"additional","affiliation":[{"name":"V Clinica Ostetrica e Ginecologica, Settore Didattico di Monza, Universit\u00e0 di Milano"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1988,2,1]]},"reference":[{"key":"bibr1-030089168807400116","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1986.tb07948.x"},{"key":"bibr2-030089168807400116","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1982.tb04692.x"},{"key":"bibr3-030089168807400116","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90179-0"},{"key":"bibr4-030089168807400116","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19821115)50:10<2024::AID-CNCR2820501008>3.0.CO;2-4"},{"key":"bibr5-030089168807400116","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(83)91202-4"},{"key":"bibr6-030089168807400116","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(86)90311-2"},{"key":"bibr7-030089168807400116","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1986.tb07815.x"},{"key":"bibr8-030089168807400116","doi-asserted-by":"publisher","DOI":"10.1038\/292551a0"},{"key":"bibr9-030089168807400116","first-page":"259","volume":"68","author":"Ohama K.","year":"1986","journal-title":"Obstet. 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