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For all these cancers a dose-response relationship has been demonstrated as well as a combination with the effect of tobacco, the two effects being multiplicative. Alcohol is also responsible for liver cancer developing on alcoholic cirrhosis. In addition, it has been suggested that alcohol consumption may be related to an increased risk of breast cancer.<\/jats:p>","DOI":"10.1177\/030089169007600404","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:41:30Z","timestamp":1523882490000},"page":"315-320","source":"Crossref","is-referenced-by-count":5,"title":["Alcohol-Related Cancers in Mediterranean Countries"],"prefix":"10.1177","volume":"76","author":[{"given":"Albert J.","family":"Tuyns","sequence":"first","affiliation":[{"name":"International Agency for Research on Cancer, Lyon, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1990,8,1]]},"reference":[{"key":"bibr1-030089169007600404","volume-title":"Data, Statistics and Maps on Cancer Mortality: Italia 1975-1977.","author":"Cislaghi C.","year":"1986"},{"key":"bibr2-030089169007600404","first-page":"264","volume-title":"In: Relevance of N-Nitroso Compounds to Human Cancer: Exposure and Mechanisms","author":"Griciute L.","year":"1987"},{"key":"bibr3-030089169007600404","first-page":"429","volume":"56","author":"Horie A.","year":"1965","journal-title":"Gann"},{"key":"bibr4-030089169007600404","volume-title":"Alcohol Drinking (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Volume 44).","author":"IARC","year":"1988"},{"key":"bibr5-030089169007600404","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910430507"},{"key":"bibr6-030089169007600404","first-page":"61","volume":"75","author":"La Vecchia C.","year":"1985","journal-title":"J. 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