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Two LCIS reoccurrences and all ipsilateral infiltrating carcinomas were observed in 37 patients treated by limited surgery. Contralateral synchronous or metachronous carcinoma was observed in 3 or 2 cases, respectively (intraductal = 3, infiltrating = 2). Three patients died of breast cancer (2 with Ipsilateral, 1 with ipsilateral and contralateral infiltrating carcinoma). The study confirms the higher risk of ipsilateral and contralateral cancer in LCIS patients and warns about the possible hazards of limited surgery in these cases.<\/jats:p>","DOI":"10.1177\/030089169207800405","type":"journal-article","created":{"date-parts":[[2018,4,23]],"date-time":"2018-04-23T11:17:17Z","timestamp":1524482237000},"page":"244-246","source":"Crossref","is-referenced-by-count":11,"title":["Risk of Infiltrating Breast Cancer Subsequent to Lobular Carcinoma in Situ"],"prefix":"10.1177","volume":"78","author":[{"given":"Stefano","family":"Ciatto","sequence":"first","affiliation":[{"name":"Centro per lo Studio e la Prevenzione Oncologica, Universit\u00e0 di Firenze, Firenze"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Cataliotti","sequence":"additional","affiliation":[{"name":"Clinica Chirurgica I, Universit\u00e0 di Firenze, Firenze"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaetano","family":"Cardona","sequence":"additional","affiliation":[{"name":"Patologia Chirurgica, Universit\u00e0 di Firenze, Firenze"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simonetta","family":"Bianchi","sequence":"additional","affiliation":[{"name":"Anatomia Patologica, Universit\u00e0 di Firenze, Firenze"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"members of the Coordinating Center and Writing Committee of FONCAM (National Task Force for Breast Cancer)","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Schittulli","sequence":"additional","affiliation":[{"name":"Bari"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Foglietta","sequence":"additional","affiliation":[{"name":"Faenza"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Di Maggio","sequence":"additional","affiliation":[{"name":"Padova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"La Grassa","sequence":"additional","affiliation":[{"name":"Padova"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Aristei","sequence":"additional","affiliation":[{"name":"Perugia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Bravetti","sequence":"additional","affiliation":[{"name":"Ravenna"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ravaioli","sequence":"additional","affiliation":[{"name":"Rimini"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Galletto","sequence":"additional","affiliation":[{"name":"Savigliano"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Amichetti","sequence":"additional","affiliation":[{"name":"Trento"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Perani","sequence":"additional","affiliation":[{"name":"Trento"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Falconieri","sequence":"additional","affiliation":[{"name":"Trieste"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1992,8,1]]},"reference":[{"key":"bibr1-030089169207800405","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(85)80251-3"},{"key":"bibr2-030089169207800405","first-page":"105","volume":"13","author":"Andersen J.","year":"1987","journal-title":"Eur. 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