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Fine needle aspiration cytology from both nodules showed highly atypical tumor cells, such as to warrant a differential diagnosis between metastatic breast cancer on the one hand and anaplastic and medullary carcinoma of the thyroid on the other. Immunophenotypic study of the neoplasm on a cell block preparation of the aspirated material showed negativity for both thyroglobulin and calcitonin; instead, the tumor cells were strongly stained with antibodies against the \u201cbreast-related\u201d markers alpha-lactalbumin and gross cystic disease fluid protein-15. Therefore, immunochemistry allowed us to establish a definite diagnosis of metastatic breast disease of the thyroid, thereby avoiding surgical procedures.<\/jats:p>","DOI":"10.1177\/030089169708300415","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:36:34Z","timestamp":1523882194000},"page":"783-787","source":"Crossref","is-referenced-by-count":10,"title":["Thyroid Metastases from a Ductal Carcinoma of the Breast. 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