{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:19:39Z","timestamp":1777918779804,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1998,1,1]],"date-time":"1998-01-01T00:00:00Z","timestamp":883612800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[1998,1]]},"abstract":"<jats:p>Glioblastoma multiforme is the most malignant tumor of the glial series. The average survival of patients with this tumor ranges from 6 to 12 months. The case of a patient who survived for more than 11 years after diagnosis of a temporal-occipital glioblastoma which was treated with surgery, radiotherapy and chemotherapy is described. The authors deduce that among patients with glioblastoma multiforme (GM), those with a long disease-free interval after initial diagnosis who undergo multimodal therapy, including aggressive tumor removal, are the most likely long-term survivors (LS). Other factors which appeared to be related to longer survival were younger age and high Karnofsky scores.<\/jats:p>","DOI":"10.1177\/030089169808400115","type":"journal-article","created":{"date-parts":[[2018,4,23]],"date-time":"2018-04-23T11:23:02Z","timestamp":1524482582000},"page":"69-74","source":"Crossref","is-referenced-by-count":18,"title":["Long-Term Survival in Cerebral Glioblastoma. Case Report and Critical Review of the Literature"],"prefix":"10.1177","volume":"84","author":[{"given":"Fabrizio","family":"Puzzilli","sequence":"first","affiliation":[{"name":"Department of Neurological Sciences, University of Rome \u201cLa Sapienza\u201d, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Ruggeri","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, University of Rome \u201cLa Sapienza\u201d, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciano","family":"Mastronardi","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, University of Rome \u201cLa Sapienza\u201d, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenica","family":"Di Stefano","sequence":"additional","affiliation":[{"name":"Department of Experimental Medicine, University of Rome \u201cLa Sapienza\u201d, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierpaolo","family":"Lunardi","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences, University of Rome \u201cLa Sapienza\u201d, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1998,1,1]]},"reference":[{"key":"bibr1-030089169808400115","first-page":"797","volume":"8","author":"Akslen L.A.","year":"1988","journal-title":"Anticancer Res.,"},{"key":"bibr2-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1967.26.1part1.0072"},{"key":"bibr3-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870501)59:9<1617::AID-CNCR2820590916>3.0.CO;2-X"},{"key":"bibr4-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19900115)65:2<337::AID-CNCR2820650226>3.0.CO;2-P"},{"key":"bibr5-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199305000-00003"},{"key":"bibr6-030089169808400115","first-page":"225","volume":"22","author":"De Tribolet N.","year":"1979","journal-title":"Neurochirurgia (Stuttg.),"},{"key":"bibr7-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3109\/02688699309103479"},{"key":"bibr8-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1965.22.4.0382"},{"key":"bibr9-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1987.67.6.0864"},{"key":"bibr10-030089169808400115","first-page":"106","volume":"27","author":"Hatanaka H.","year":"1984","journal-title":"Neurochirurgia (Stuttg.),"},{"key":"bibr11-030089169808400115","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/j.1699-0463.1989.tb00829.x","volume":"97","author":"Helset A.","year":"1989","journal-title":"APMIS,"},{"key":"bibr12-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1007\/BF01324695"},{"key":"bibr13-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1126\/science.1905840"},{"key":"bibr14-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1989.71.3.0335"},{"key":"bibr15-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199201000-00010"},{"key":"bibr16-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410280614"},{"key":"bibr17-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1992.273"},{"key":"bibr18-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1967.27.5.0388"},{"key":"bibr19-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3639.1993.tb00753.x"},{"key":"bibr20-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-84988-6"},{"key":"bibr21-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810215)47:4<649::AID-CNCR2820470405>3.0.CO;2-W"},{"key":"bibr22-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199401000-00002"},{"key":"bibr23-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19890201)63:3<524::AID-CNCR2820630321>3.0.CO;2-D"},{"key":"bibr24-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1988.308"},{"key":"bibr25-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1007\/BF00165483"},{"key":"bibr26-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1986.65.6.0799"},{"key":"bibr27-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1950.7.3.0261"},{"key":"bibr28-030089169808400115","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1007\/BF01050258","volume":"15","author":"Pardo F.S.","year":"1993","journal-title":"J. Neuro-Oncol.,"},{"key":"bibr29-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3109\/02688699309023808"},{"key":"bibr30-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19891115)64:10<1984::AID-CNCR2820641003>3.0.CO;2-S"},{"key":"bibr31-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1960.17.4.0736"},{"key":"bibr32-030089169808400115","first-page":"813","volume":"74","author":"Rutz H.P.","year":"1991","journal-title":"Case report. J. Neurosurg.,"},{"key":"bibr33-030089169808400115","first-page":"716","volume":"5","author":"Salcman M.","year":"1993","journal-title":"Neurosurgery,"},{"key":"bibr34-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1988.69.4.0506"},{"key":"bibr35-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1007\/BF01401926"},{"key":"bibr36-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3109\/02841869009096382"},{"key":"bibr37-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1978.49.3.0333"},{"key":"bibr38-030089169808400115","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199409000-00010"},{"key":"bibr39-030089169808400115","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1989.71.4.0487"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089169808400115","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089169808400115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:46:01Z","timestamp":1777661161000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030089169808400115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,1]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1998,1]]}},"alternative-id":["10.1177\/030089169808400115"],"URL":"https:\/\/doi.org\/10.1177\/030089169808400115","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,1]]}}}