{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:19:59Z","timestamp":1777918799356,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1998,7,1]],"date-time":"1998-07-01T00:00:00Z","timestamp":899251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tumori"],"published-print":{"date-parts":[[1998,7]]},"abstract":"<jats:sec>\n                    <jats:title>Aims and background<\/jats:title>\n                    <jats:p>The aim of the study was to report and discuss a historical series of neoplastic and non-neoplastic lesions of the thyroid gland obtained at autopsy that were examined between 1931 and 1989 at the Pathology Department of the Medical School of the University of SaTo Paulo.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Records of 145,043 cases were reviewed to select those affecting the thyroid gland. The slides of these selected cases were analyzed and classified according to the current terminology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Non-neoplastic lesions comprised 91.62% of the cases (n=4647), and most of them were adenomatous goiter (n=3014). Neoplastic lesions were divided into two groups: primary and metastatic. Of the 282 primary tumors, 135 were benign and 147 were malignant. Among the malignant neoplasms, the most frequent types were follicular, papillary and undifferentiated (n=39, 36 and 29, respectively). The most frequent tumor types among the metastatic neoplasms were lymphoproliferative processes and carcinomas (n=67 and 34, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We conclude that, because of the high frequency of neoplastic lesions (8.38%), 68.24% of which were malignant, detailed examination of the thyroid by pathological methods should be carefully and systematically performed for the accurate detection of thyroid lesions, especially carcinomas.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/030089169808400412","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T12:20:17Z","timestamp":1523881217000},"page":"499-503","source":"Crossref","is-referenced-by-count":4,"title":["Neoplastic and Non-neoplastic Thyroid Lesions in Autopsy Material: Historical Review of Six Decades in S\u00e3o Paulo, Brazil"],"prefix":"10.1177","volume":"84","author":[{"given":"H\u00e9lio","family":"Bisi","sequence":"first","affiliation":[{"name":"Pathology Department, School of Medicine, University of S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gl\u00e1ucia Berreta","family":"Ruggeri","sequence":"additional","affiliation":[{"name":"Pathology Department, School of Medicine, University of S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adhemar Longatto","family":"Filho","sequence":"additional","affiliation":[{"name":"Pathology Division, Instituto Adolfo Lutz, S\u00e3o Paulo, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosalinda Y.","family":"Asato de Camargo","sequence":"additional","affiliation":[{"name":"Pathology Department, School of Medicine, University of S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vilma S.O.","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Pathology Department, School of Medicine, University of S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anete H.","family":"Abdo","sequence":"additional","affiliation":[{"name":"Pathology Department, School of Medicine, University of S\u00e3o Paulo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1998,7,1]]},"reference":[{"key":"bibr1-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197806)41:6<2267::AID-CNCR2820410627>3.0.CO;2-7"},{"key":"bibr2-030089169808400412","first-page":"181","volume":"39","author":"Al-Moussa M.","year":"1979","journal-title":"J. Clin. Pathol."},{"key":"bibr3-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-595X(79)80016-X"},{"key":"bibr4-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19891101)64:9<1888::AID-CNCR2820640922>3.0.CO;2-C"},{"key":"bibr5-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1177\/030089169508100115"},{"key":"bibr6-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/83.2.135"},{"key":"bibr7-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-13-7-801"},{"key":"bibr8-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196901)23:1<230::AID-CNCR2820230131>3.0.CO;2-N"},{"key":"bibr9-030089169808400412","first-page":"1214","volume-title":"In: Robbins pathologic basis of disease,","author":"DeLellis R.A.","year":"1994","edition":"5"},{"key":"bibr10-030089169808400412","first-page":"232","volume":"51","author":"Farooki M.A.","year":"1969","journal-title":"Part I: Material and methods and results. Int. Surg."},{"key":"bibr11-030089169808400412","first-page":"317","volume":"51","author":"Farooki M.A.","year":"1969","journal-title":"Part II: Discussion. Int. Surg."},{"key":"bibr12-030089169808400412","first-page":"103","volume-title":"In: Tumors of the thyroid gland.","author":"Gowing N.F.C.","year":"1970"},{"key":"bibr13-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711100405"},{"key":"bibr14-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/25.3.289"},{"key":"bibr15-030089169808400412","volume-title":"International histological classification of tumours, World Health Organization","author":"Hedinger C.","year":"1988"},{"key":"bibr16-030089169808400412","first-page":"2329","volume":"37","author":"Heitz P.","year":"1976","journal-title":"A study of 573 thyroid tumors and 161 autopsy cases observed over a thirty-year period. Cancer"},{"key":"bibr17-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197303000-00003"},{"key":"bibr18-030089169808400412","first-page":"291","volume":"59","author":"Hull O.H.","year":"1955","journal-title":"Arch. Pathol."},{"key":"bibr19-030089169808400412","first-page":"521","volume":"55","author":"Kapp D.S.","year":"1982","journal-title":"Yale J. Biol. Med."},{"key":"bibr20-030089169808400412","first-page":"457","volume":"4","author":"Kurashima C.","year":"1985","journal-title":"Survey Synth. Pathol. Res."},{"key":"bibr21-030089169808400412","first-page":"405","volume":"60","author":"Leelachaikul P.","year":"1977","journal-title":"J. Med. Assoc. Thai."},{"key":"bibr22-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(85)90167-9"},{"key":"bibr23-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-15-10-1270"},{"key":"bibr24-030089169808400412","first-page":"297","volume-title":"Tumors of the thyroid gland, Fasc. 5, Third series,","author":"Rosai J.","year":"1992"},{"key":"bibr25-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198411000-00001"},{"key":"bibr26-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(88)80102-5"},{"key":"bibr27-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196205\/06)15:3<557::AID-CNCR2820150315>3.0.CO;2-H"},{"key":"bibr28-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197905)43:5<1702::AID-CNCR2820430521>3.0.CO;2-S"},{"key":"bibr29-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197701)39:1<215::AID-CNCR2820390134>3.0.CO;2-#"},{"key":"bibr30-030089169808400412","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-17-2-201"}],"container-title":["Tumori Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089169808400412","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/030089169808400412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:46:35Z","timestamp":1777661195000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/030089169808400412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,7]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1998,7]]}},"alternative-id":["10.1177\/030089169808400412"],"URL":"https:\/\/doi.org\/10.1177\/030089169808400412","relation":{},"ISSN":["0300-8916","2038-2529"],"issn-type":[{"value":"0300-8916","type":"print"},{"value":"2038-2529","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,7]]}}}