{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:21:37Z","timestamp":1777918897082,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2010,6,29]],"date-time":"2010-06-29T00:00:00Z","timestamp":1277769600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Pathol"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:p>This report presents a rare, spontaneous, heterologous, malignant mixed M\u00fcllerian tumor observed in a 98-week-old untreated Wistar rat. At necropsy, the right uterine horn was dilated and contained a mass of approximately 10 \u00d7 15 mm. Histopathologically the mass consisted of 2 parts with different morphologic characteristics, a polypoid mass protruding into the uterine lumen and a more solid part that replaced the adjacent uterine wall. The solid part exhibited characteristics of a highly infiltrative adenocarcinoma, whereas the composition of the polypoid mass was heterogeneous, consisting of a variety of benign and malignant epithelial and mesenchymal elements. The epithelial components included well-differentiated endometrial and squamous epithelium juxtaposed to carcinosarcomatous areas. The mesenchymal components consisted of well-differentiated cartilage and bone along with chondrosarcomatous, rhabdomyomatous, and other mesenchymal elements. Immunohistochemical analysis further supported the diagnosis of malignant mixed M\u00fcllerian tumor.<\/jats:p>","DOI":"10.1177\/0300985810374840","type":"journal-article","created":{"date-parts":[[2010,6,29]],"date-time":"2010-06-29T22:10:20Z","timestamp":1277849420000},"page":"1105-1110","source":"Crossref","is-referenced-by-count":9,"title":["Spontaneous Malignant Mixed M\u00fcllerian Tumor in a Wistar Rat"],"prefix":"10.1177","volume":"47","author":[{"given":"H.","family":"van den Brink-Knol","sequence":"first","affiliation":[{"name":"Pathology Group, Department of Toxicology, NOTOX BV,\u2019s-Hertogenbosch, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"van Esch","sequence":"additional","affiliation":[{"name":"Department of Toxicology and Drug Disposition, MSD, Oss, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,6,29]]},"reference":[{"key":"bibr1-0300985810374840","first-page":"361","volume-title":"Pathology of the Female Reproductive Tract","author":"Anderson MC","year":"2002","edition":"1"},{"key":"bibr2-0300985810374840","doi-asserted-by":"publisher","DOI":"10.1016\/S0940-2993(99)80133-X"},{"key":"bibr3-0300985810374840","first-page":"431","volume":"103","author":"Ernst H","year":"1990","journal-title":"Berl M\u00fcnch Tierartzl Wochenschr"},{"key":"bibr4-0300985810374840","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(77)90071-8"},{"key":"bibr5-0300985810374840","doi-asserted-by":"publisher","DOI":"10.1354\/vp.43-4-560"},{"key":"bibr6-0300985810374840","doi-asserted-by":"publisher","DOI":"10.1177\/019262339001800309"},{"key":"bibr7-0300985810374840","first-page":"443","volume-title":"Pathology of the Fischer rat","author":"Leininger JR","year":"1990","edition":"1"},{"key":"bibr8-0300985810374840","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.55.5.321"},{"key":"bibr9-0300985810374840","unstructured":"International Classification of Rodent Tumours Part I: The Rat, Volume 9: Female Genital Tract, ed. Mohr U, 1st ed., pp. 58\u201359. IARC Scientific Publications, Lyon, France, 1997."}],"container-title":["Veterinary Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300985810374840","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0300985810374840","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0300985810374840","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T18:49:18Z","timestamp":1777661358000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0300985810374840"}},"subtitle":["A Case Report Including Immunohistochemistry"],"short-title":[],"issued":{"date-parts":[[2010,6,29]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["10.1177\/0300985810374840"],"URL":"https:\/\/doi.org\/10.1177\/0300985810374840","relation":{},"ISSN":["0300-9858","1544-2217"],"issn-type":[{"value":"0300-9858","type":"print"},{"value":"1544-2217","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,29]]}}}